Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 17/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.56 |
| ▸ | HPGD | P15428 | 7/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | ATM | Q13315 | 3/20 | 0.56 |
| ▸ | GLA | P06280 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2890796 | 0.90 | MAPT (0.46) | KDM4EALDH1A1HPGDGAAATM | |
| SCHEMBL30779358 | 0.90 | MAPT (0.46) | KDM4EALDH1A1HPGDGAAATM | |
| SCHEMBL4502703 | 0.89 | KDM4E (0.48) | KDM4EALDH1A1HPGDGAAATM | |
| SCHEMBL7399477 | 0.87 | KDM4E (0.63) | KDM4EALDH1A1HPGDGAAATM | |
| SCHEMBL16318447 | 0.85 | KDM4E (0.52) | KDM4EALDH1A1HPGDGAAATM | |
| SCHEMBL10318265 | 0.83 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDGAAATM | |
| SCHEMBL2934675 | 0.83 | CA12 (0.54) | KDM4EALDH1A1HPGDGAAATM | |
| SCHEMBL4490699 | 0.82 | KDM4E (0.49) | KDM4EALDH1A1HPGDGAAATM | |
| SCHEMBL30816858 | 0.82 | KDM4E (0.49) | KDM4EALDH1A1HPGDGAAATM | |
| SCHEMBL31480211 | 0.82 | KDM4E (0.49) | KDM4EALDH1A1HPGDGAAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1166668-C | Method for preparing substituted [1,4] diazepino (6,7,1-hi) indol-4-ones | ��ʲ | 2004-09-15 | — | — | CN | disclosed |
| US-6689881-B1 | Method for preparing substituted [1,4]diazepino[6,7,1-hi]indol-4-ones | WARNER-LAMBERT LLC | 2004-02-10 | — | — | US | disclosed |
| CN-1362960-A | Process for the preparation of substituted [1,4] -diaza * o [6,7, 1-hi ] -indol-4-ones | WARNER LAMBERT CO (US) | 2002-08-07 | — | — | CN | disclosed |