Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6741692 | 1.00 | ITGA4 (0.52) | ITGA4ITGB1 | |
| SCHEMBL6744662 | 0.93 | ITGA4 (0.46) | ITGA4ITGB1 | |
| SCHEMBL6744659 | 0.93 | ITGA4 (0.46) | ITGA4ITGB1 | |
| SCHEMBL6743762 | 0.89 | ITGA4 (0.51) | ITGA4ITGB1 | |
| SCHEMBL6741690 | 0.80 | ITGA4 (0.43) | ITGA4ITGB1 | |
| SCHEMBL6742874 | 0.80 | ITGA4 (0.52) | ITGA4ITGB1 | |
| SCHEMBL6745455 | 0.75 | ITGA4 (0.48) | ITGA4ITGB1 | |
| SCHEMBL5158287 | 0.72 | ITGA4 (0.64) | ITGA4ITGB1 | |
| SCHEMBL3722481 | 0.72 | ITGA4 (0.67) | ITGA4ITGB1 | |
| SCHEMBL3722480 | 0.72 | ITGA4 (0.67) | ITGA4ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6685617-B1 | 4-(((-1-CARBOXY-2-(4-((2,6-DICHLOROBENZOYL)AMINE)PHENYL)ETHYL) AMINO)CARBONYL)-3-OXO-3-THIAZOLIDINEBUTANOIC ACID, USED AS ANTAGONISTS FOR CELLULAR ADHESION MOLECULES, AND ADMINISTERED AS ANTIINFLAMMATORY AGENTS | PHARMACIA & UPJOHN COMPANY | 2004-02-03 | — | — | US | disclosed |
| EP-1089989-A1 | INHIBITORS OF ALPHA4BETA1 MEDIATED CELL ADHESION | PHARMACIA & UPJOHN COMPANY (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999067230-A1 | INHIBITORS OF α4β1 MEDIATED CELL ADHESION | PHARMACIA & UPJOHN COMPANY (US) | 1999-12-29 | — | — | WO | disclosed |