Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TERT | O14746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11478803 | 0.88 | HTT (0.45) | HSD17B2HTTALDH1A1TSHRHPGD | |
| SCHEMBL11478359 | 0.83 | HPGD (0.47) | HSD17B2HTTALDH1A1TSHRHPGD | |
| SCHEMBL10685501 | 0.76 | LMNA (0.58) | HSD17B2HTTALDH1A1TSHRLMNA | |
| SCHEMBL11484201 | 0.75 | KMT2A (0.56) | ALDH1A1TSHRHSD17B10L3MBTL1MAPT | |
| SCHEMBL11479137 | 0.75 | CA1 (0.55) | HSD17B2TSHRLMNAL3MBTL1CYP1A2 | |
| SCHEMBL11490506 | 0.75 | KMT2A (0.61) | ALDH1A1HPGDKDM4EL3MBTL1POLB | |
| SCHEMBL11478920 | 0.74 | HSD17B2 (0.52) | HSD17B2HTTALDH1A1TSHRHPGD | |
| SCHEMBL11475018 | 0.73 | KMT2A (0.48) | ALDH1A1HSD17B10L3MBTL1POLBMAPT | |
| SCHEMBL24564668 | 0.72 | MAPT (0.60) | ALDH1A1TSHRHPGDKDM4ENPC1 | |
| SCHEMBL15091391 | 0.72 | MAPT (0.60) | ALDH1A1TSHRHPGDKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6685617-B1 | 4-(((-1-CARBOXY-2-(4-((2,6-DICHLOROBENZOYL)AMINE)PHENYL)ETHYL) AMINO)CARBONYL)-3-OXO-3-THIAZOLIDINEBUTANOIC ACID, USED AS ANTAGONISTS FOR CELLULAR ADHESION MOLECULES, AND ADMINISTERED AS ANTIINFLAMMATORY AGENTS | PHARMACIA & UPJOHN COMPANY | 2004-02-03 | — | — | US | disclosed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
| US-4219560-A | ANTILIPEMIC AGENTS | SANDOZ, INC. (US) | 1980-08-26 | — | — | US | disclosed |