Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.51 |
| ▸ | PPARA | Q07869 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 4/20 | 0.39 |
| ▸ | MMP13 | P45452 | 4/20 | 0.39 |
| ▸ | MMP9 | P14780 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPRA | P18433 | 1/20 | 0.39 |
| ▸ | PTPRB | P23467 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16754032 | 1.00 | PPARG (0.51) | PPARGPPARASMN1; SMN2HIF1ACES1 | |
| SCHEMBL7284495 | 0.84 | PPARG (0.54) | PPARGPPARASMN1; SMN2HIF1AMMP1 | |
| SCHEMBL16753617 | 0.81 | PPARA (0.37) | PPARGPPARAALDH1A1CA12 | |
| SCHEMBL605141 | 0.77 | PPARG (0.47) | PPARGPPARASMN1; SMN2MMP1MMP13 | |
| SCHEMBL3272549 | 0.76 | PPARG (0.59) | PPARGPPARASMN1; SMN2HIF1ACES1 | |
| SCHEMBL3272547 | 0.76 | PPARG (0.59) | PPARGPPARASMN1; SMN2HIF1ACES1 | |
| Aniline SCHEMBL2334841 | 0.75 | SLC6A2 (0.42) | SMN1; SMN2HIF1ACES1TSHRSLC6A2 | |
| SCHEMBL17044978 | 0.75 | CES1 (0.39) | PPARGPPARASMN1; SMN2HIF1ACES1 | |
| SCHEMBL7022118 | 0.75 | PPARG (0.40) | PPARGPPARASMN1; SMN2HIF1ACES1 | |
| SCHEMBL700953 | 0.74 | ADORA3 (0.33) | PPARGPPARAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040131551-A1 | Enhanced relaxivity monomeric and multimeric compounds | BRISTOL-MYERS SQUIBB COMPANY | 2004-07-08 | — | — | US | disclosed |
| US-6693190-B1 | TETRAAZACYCLODODECANE MACROCYCLE DERIVATIVES INCLUDING METAL COMPLEXES; MAGNETIC RESONANCE IMAGING AGENTS | BRACCO INTERNATIONAL B.V. (NL) | 2004-02-17 | — | — | US | disclosed |
| EP-0670832-B1 | HEPATOBILIARY MAGNETIC RESONANCE CONTRAST AGENTS | BRACCO INT BV (NL) | 2002-06-05 | — | — | EP | disclosed |
| EP-1184377-A1 | Hepatobiliary magnetic resonance contrast agents | BRACCO International B.V. (NL) | 2002-03-06 | — | — | EP | disclosed |
| EP-0708761-A1 | ENHANCED RELAXIVITY MONOMERIC AND MULTIMERIC COMPOUNDS | BRACCO International B.V. (NL) | 1996-05-01 | — | — | EP | disclosed |
| WO-1995031444-A1 | ENHANCED RELAXIVITY MONOMERIC AND MULTIMERIC COMPOUNDS | BRACCO INTERNATIONAL B.V. (NL) | 1995-11-23 | — | — | WO | disclosed |
| US-5358704-A | Hepatobiliary tetraazamacrocyclic magnetic resonance contrast agents | BRISTOL-MYERS SQUIBB (US) | 1994-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040131551-A1 | Enhanced relaxivity monomeric and multimeric compounds | H1-2, H1-0, H1-3 | PPARG 4718/4885PPARA 4590/4885SMN1; SMN2 1401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.