SCHEMBL6741865

SCHEMBL6741865

CCCc1ccc2cc3cc(C)c(F)c(F)c3cc2c1

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.38
CNR2 P34972 1/20 0.38
NCEH1 Q6PIU2 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2A6 P11509 1/20 0.33
SKP2 Q13309 1/20 0.32
ALOX5 P09917 1/20 0.31
SIGMAR1 Q99720 1/20 0.30
BDKRB2 P30411 1/20 0.30
MEN1 O00255 1/20 0.30
POLB P06746 1/20 0.30
GAA P10253 1/20 0.30
KMT2A Q03164 1/20 0.30
FFAR4 Q5NUL3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6731145 0.91 SKP2 (0.43) CYP1A2SKP2SIGMAR1BDKRB2
SCHEMBL6736827 0.90 SKP2 (0.39) SKP2BDKRB2
SCHEMBL6736855 0.88 CYP1A2 (0.46) CYP1A2CYP2A6MEN1POLBGAA
SCHEMBL6737669 0.86 CNR1 (0.39) CNR1CNR2NCEH1CYP1A2CYP2A6
SCHEMBL6738566 0.86 CNR1 (0.39) CNR1CNR2NCEH1CYP1A2CYP2A6
SCHEMBL6736746 0.84 CNR1 (0.37) CNR1CNR2NCEH1CYP1A2CYP2A6
SCHEMBL6731332 0.81 TLR8 (0.35) CNR1CNR2NCEH1SKP2ALOX5
SCHEMBL6735447 0.80 TLR8 (0.40) CNR1CNR2ALOX5BDKRB2MEN1
SCHEMBL6741609 0.78 SKP2 (0.36) SKP2ALOX5SIGMAR1BDKRB2
SCHEMBL6736230 0.78 SKP2 (0.37) CYP1A2CYP2A6SKP2SIGMAR1BDKRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6682785-B2 A FLUOROANTHRACENE COMPOUNDS; HEAT RESISTANCE, RADIATION RESISTANCE, PHOTOSTABILITY CLARIANT FINANCE (BVI) LIMITED (VG) 2004-01-27 US disclosed
US-20030118749-A1 A fluoroanthracene compounds; heat resistance, radiation resistance, photostability CLARIANT INTERNATIONAL LTD. 2003-06-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030118749-A1 A fluoroanthracene compounds; heat resistance, radiation resistance, photostability HSF1, ABCC1, FLNA CNR1 2742/4885CNR2 3959/4885NCEH1 4334/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.