Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | AGER | Q15109 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30821243 | 1.00 | MAPT (0.53) | MAPTGAAKMT2AHTTHSD17B10 | |
| SCHEMBL20558075 | 0.86 | GRM4 (0.49) | MAPTGAAALDH1A1TLR7KDM4E | |
| SCHEMBL128343 | 0.80 | KDM4E (0.61) | MAPTGAAALDH1A1TLR7KDM4E | |
| SCHEMBL30504303 | 0.79 | ATR (0.57) | MAPTGAAKMT2AHTTHSD17B10 | |
| SCHEMBL187899 | 0.79 | ALDH1A1 (0.55) | MAPTGAAKMT2AMEN1ALDH1A1 | |
| SCHEMBL5682288 | 0.79 | ATR (0.57) | MAPTGAAKMT2AHTTHSD17B10 | |
| SCHEMBL2280224 | 0.79 | KDM4E (0.59) | MAPTGAAALDH1A1TLR7KDM4E | |
| SCHEMBL29262306 | 0.79 | KDM4E (0.59) | MAPTGAAKMT2AMEN1ALDH1A1 | |
| SCHEMBL17263069 | 0.78 | KMT2A (0.52) | MAPTKMT2AHTTMEN1ALDH1A1 | |
| SCHEMBL20385460 | 0.78 | KMT2A (0.52) | MAPTGAAKMT2AHTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10398706-B2 | Heteroaryldiazepine derivatives as RSV inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2019-09-03 | — | — | US | disclosed |
| US-20180193352-A1 | HETEROARYLDIAZEPINE DERIVATIVES AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. | 2018-07-12 | — | — | US | disclosed |
| US-20180193352-A1 | HETEROARYLDIAZEPINE DERIVATIVES AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. | 2018-07-12 | — | — | US | disclosed |
| WO-2018129287-A1 | HETEROARYLDIAZEPINE DERIVATIVES AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2018-07-12 | — | — | WO | disclosed |
| US-20150190504-A1 | WOUND HEALING | KINETIC CONCEPTS, INC. | 2015-07-09 | — | — | US | disclosed |
| US-8957076-B2 | Wound healing | SYSTAGENIX WOUND MANAGEMENT (US), INC. (US) | 2015-02-17 | — | — | US | disclosed |
| US-8063052-B2 | Wound healing | SYSTAGENIX WOUND MANAGEMENT (US), INC. (US) | 2011-11-22 | — | — | US | disclosed |
| US-20100099622-A1 | WOUND HEALING | SYSTAGENIX WOUND MANAGEMENT (US), INC. (US) | 2010-04-22 | — | — | US | disclosed |
| US-20090170910-A1 | WOUND HEALING | KCI USA, INC. | 2009-07-02 | — | — | US | disclosed |
| US-7326788-B2 | Selective, potent small molecule protein tyrosine kinase inhibitors; such as 6-chloro-3-(3-methyl-isoxazol-5-yl)-4-(pyridin-4-yl)-1H-quinolin-2-one | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-02-05 | — | — | US | disclosed |
| EP-1660087-A2 | QUINOLINONE DERIVATIVES AS INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-05-31 | — | — | EP | disclosed |
| WO-2006028836-A1 | WOUND HEALING | ETHICON, INC. (US) | 2006-03-16 | — | — | WO | disclosed |
| US-6919336-B2 | Hallogenated aminobenzophenones and aminobenzoylpyridines as inhibitors of IL-1 and TNF | NOVARTIS AG (CH) | 2005-07-19 | — | — | US | disclosed |
| US-20050049274-A1 | Quinolinone derivatives as inhibitors of c-fms kinase | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-03-03 | — | — | US | disclosed |
| WO-2005009967-A2 | QUINOLINONE DERIVATIVES AS INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-02-03 | — | — | WO | disclosed |
| US-20040097731-A1 | Hallogenated aminobenzophenones and aminobenzoylpyridines as inhibitors of il-1and tnf | NOVARTIS AG (CH) | 2004-05-20 | — | — | US | disclosed |
| US-4207322-A | 6-Aryl-s-triazolo-(4,3-alpha)-pyrido-(2,3-f)-(1,4)-diazepines | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1980-06-10 | — | — | US | disclosed |
| US-4110455-A | 6-ARYL-S-TRIAZOLO-(4,3-A)-PYRIDO-(2,3-F)-1,4-DIAZEPINES | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1978-08-29 | — | — | US | disclosed |
| US-4012397-A | 2-Benzoyl-3-amino-pyridines | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1977-03-15 | — | — | US | disclosed |
| US-3969361-A | 2-Benzoyl-3-amino-pyridines | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1976-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10398706-B2 | Heteroaryldiazepine derivatives as RSV inhibitors | CYP3A5, CYP3A43, CYP3A4 | MAPT 3236/4885GAA 1774/4885KMT2A 649/4885 |
| US-20100099622-A1 | WOUND HEALING | MAPK1, MAPK3, MAPK4 | MAPT 3256/4885GAA 4803/4885KMT2A 4281/4885 |
| US-20040097731-A1 | Hallogenated aminobenzophenones and aminobenzoylpyridines as inhibitors of il-1and tnf | TNF, NFKBIA, IL1A | MAPT 2379/4885GAA 1202/4885KMT2A 1573/4885 |
| US-20050049274-A1 | Quinolinone derivatives as inhibitors of c-fms kinase | FLT3, ABL1, FES | MAPT 472/4885GAA 4452/4885KMT2A 1469/4885 |
| US-20090170910-A1 | WOUND HEALING | MAPK1, MAPK3, MAPK4 | MAPT 3256/4885GAA 4803/4885KMT2A 4281/4885 |
| US-20150190504-A1 | WOUND HEALING | MAPK1, MAPK3, MAPK4 | MAPT 3256/4885GAA 4803/4885KMT2A 4281/4885 |
| US-20180193352-A1 | HETEROARYLDIAZEPINE DERIVATIVES AS RSV INHIBITORS | CYP3A5, CYP3A43, CYP3A4 | MAPT 3236/4885GAA 1774/4885KMT2A 649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.