SCHEMBL6742136

SCHEMBL6742136

C=Cc1ccc(C(O)c2ccc(OC)cc2OC)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.44
TRPA1 O75762 1/20 0.44
CYP1A1 P04798 4/20 0.42
CYP1A2 P05177 4/20 0.42
CYP1B1 Q16678 4/20 0.42
NFE2L2 Q16236 1/20 0.42
BCHE P06276 1/20 0.42
TYR P14679 1/20 0.42
ACHE P22303 1/20 0.42
ADRA2A P08913 2/20 0.41
ADRA1A P35348 2/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
ABCG2 Q9UNQ0 2/20 0.40
CYP2D6 P10635 1/20 0.40
MAPT P10636 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29541486 0.89 FFAR1 (0.46) BCHETYRACHEMAPT
SCHEMBL10686479 0.88 LMNA (0.54) LMNACYP1A1CYP1A2CYP1B1BCHE
SCHEMBL7145569 0.85 LMNA (0.46) LMNACYP1A1CYP1A2CYP1B1BCHE
SCHEMBL131894 0.83 BCHE (0.51) LMNACYP1A1CYP1A2CYP1B1BCHE
SCHEMBL131893 0.82 LMNA (0.49) LMNABCHETYRACHEADRA2A
SCHEMBL6550407 0.81 MEN1 (0.48) LMNACYP1A1CYP1A2CYP1B1BCHE
SCHEMBL2096168 0.81 CA12 (0.56) CYP1A1CYP1A2CYP1B1BCHETYR
SCHEMBL5367689 0.78 LMNA (0.43) LMNACYP1A1CYP1A2CYP1B1BCHE
SCHEMBL16335562 0.77 BCHE (0.43) LMNABCHETYRACHEADRA2A
SCHEMBL3924349 0.77 CA12 (0.56) CYP1A1CYP1A2CYP1B1BCHETYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6770406-B1 Imaging element containing a polymeric benzylic blocked developer EASTMAN KODAK COMPANY 2004-08-03 US disclosed
US-20040137380-A1 IMAGING ELEMENT CONTAINING A POLYMERIC BENZYLIC BLOCKED DEVELOPER EASTMAN KODAK COMPANY 2004-07-15 US disclosed