Diclocymet

Diclocymet

SCHEMBL674274

C[C@@H](NC(=O)[C@H](C#N)C(C)(C)C)c1ccc(Cl)cc1Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
LMNA P02545 1/20 0.46
POLB P06746 1/20 0.46
MAPT P10636 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diclocymet SCHEMBL42437 1.00 MEN1 (0.50) MEN1KMT2ALMNAPOLBMAPT
Diclocymet SCHEMBL674273 1.00 MEN1 (0.50) MEN1KMT2ALMNAPOLBMAPT
Diclocymet SCHEMBL8921616 1.00 MEN1 (0.50) MEN1KMT2ALMNAPOLBMAPT
Diclocymet SCHEMBL4165786 1.00 MEN1 (0.50) MEN1KMT2ALMNAPOLBMAPT
SCHEMBL15144396 0.90 MEN1 (0.48) MEN1KMT2ALMNAPOLBMAPT
Diclocymet SCHEMBL6052765 0.89 MEN1 (0.42) MEN1KMT2ALMNAMAPTL3MBTL1
SCHEMBL9214484 0.88 MAPK1 (0.43) MEN1KMT2A
SCHEMBL19908124 0.84 MEN1 (0.52) MEN1KMT2ALMNAPOLBMAPT
Diclocymet SCHEMBL2486533 0.83 SMN1; SMN2 (0.44) MEN1KMT2ALMNAL3MBTL1
SCHEMBL12143440 0.77 MEN1 (0.47) MEN1KMT2ALMNAPOLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9249631-A None JP disclosed
JP-9249631-A None JP disclosed
JP-10338604-A None JP disclosed
US-20220168278-A1 LOW DOSE FLURALANER COMPOSITIONS FOR PROTECTION AGAINST PARASITIC INVERTEBRATE PEST VIRBAC (FR) 2022-06-02 US disclosed
EP-3927341-A1 LOW DOSE FLURALANER COMPOSITIONS FOR PROTECTION AGAINST PARASITIC INVERTEBRATE PEST VIRBAC (FR) 2021-12-29 EP disclosed
US-10899932-B2 Non-amphoteric, quaternisable and water-soluble polymers for modifying the surface charge of solid particles BASF SE (DE) 2021-01-26 US disclosed
WO-2020201440-A1 LOW DOSE FLURALANER COMPOSITIONS FOR PROTECTION AGAINST PARASITIC INVERTEBRATE PEST VIRBAC (FR) 2020-10-08 WO disclosed
US-10759767-B2 Compositions comprising a triazole compound BASF Agro B.V. (NL) 2020-09-01 US disclosed
EP-3646731-A1 PESTICIDAL MIXTURES COMPRISING A PYRAZOLE COMPOUND BASF SE (DE) 2020-05-06 EP disclosed
EP-3300602-B1 PESTICIDAL MIXTURES COMPRISING A PYRAZOLE COMPOUND BASF SE (DE) 2020-03-25 EP disclosed
EP-1166630-B1 Solid pesticidal formulation SUMITOMO CHEMICAL CO (JP) 2003-07-09 EP disclosed
US-6541425-B1 Sustained release; fungicide, herbicide, insecticide BASF AKTIENGESELLSCHAFT (DE) 2003-04-01 US disclosed
JP-2003081712-A METHOD FOR CONTROLLING DISEASE INJURY OF RICE PLANT SEEDLING SUMITOMO CHEM CO LTD 2003-03-19 JP disclosed
US-20020019441-A1 Solid pesticidal formulation SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-02-14 US disclosed
EP-1166630-A1 Solid pesticidal formulation SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-01-02 EP disclosed
EP-1083790-A1 RETARDING FORMULATIONS OF ACTIVE SUBSTANCES USED FOR PLANT PROTECTION BASF AKTIENGESELLSCHAFT (DE) 2001-03-21 EP disclosed
WO-1999056540-A1 RETARDING FORMULATIONS OF ACTIVE SUBSTANCES USED FOR PLANT PROTECTION BASF AKTIENGESELLSCHAFT (DE) 1999-11-11 WO disclosed
JP-H10338604-A COMPOSITION FOR CONTROLLING DISEASE DAMAGE OF PADDY RICE PLANT AND CONTROL USED THEREFOR SUMITOMO CHEM CO LTD 1998-12-22 JP disclosed
JP-H09249631-A PRODUCTION OF N-((R)-1-(2,4-DICHLOROPHENYL)ETHYL)-(S)-2-CYANO-3,3-DIMETHYLBUTANAMIDE SUMITOMO CHEM CO LTD 1997-09-22 JP disclosed
JP-H09249631-A PRODUCTION OF N-((R)-1-(2,4-DICHLOROPHENYL)ETHYL)-(S)-2-CYANO-3,3-DIMETHYLBUTANAMIDE SUMITOMO CHEM CO LTD 1997-09-22 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220168278-A1 LOW DOSE FLURALANER COMPOSITIONS FOR PROTECTION AGAINST PARASITIC INVERTEBRATE PEST P2RX7, CAT, PDE8A MEN1 2904/4885KMT2A 1069/4885LMNA 2657/4885
US-10759767-B2 Compositions comprising a triazole compound CYP1B1, CYP3A5, CYP4B1 MEN1 2165/4885KMT2A 2664/4885LMNA 3497/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.