SCHEMBL6742755

SCHEMBL6742755

CCCCc1cccc(OPO)c1CCCC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 5/20 0.46
ALOX5 P09917 1/20 0.46
PPARA Q07869 2/20 0.41
LTB4R Q15722 1/20 0.40
LTB4R2 Q9NPC1 1/20 0.40
PPARG P37231 1/20 0.40
THRA P10827 1/20 0.38
THRB P10828 1/20 0.38
LIPG Q9Y5X9 1/20 0.37
ELANE P08246 1/20 0.36
CTSG P08311 1/20 0.36
HPGD P15428 2/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
NPC1 O15118 1/20 0.36
MAPK1 P28482 1/20 0.36
HTT P42858 1/20 0.36
RAB9A P51151 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
APLNR P35414 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6745888 0.94 PTGS2 (0.51) PTGS2ALOX5PPARALTB4RLTB4R2
SCHEMBL28561423 0.94 PTGS2 (0.51) PTGS2ALOX5PPARALTB4RLTB4R2
SCHEMBL1965861 0.94 PTGS2 (0.51) PTGS2ALOX5PPARALTB4RLTB4R2
SCHEMBL4443931 0.94 PTGS2 (0.51) PTGS2ALOX5PPARALTB4RLTB4R2
SCHEMBL6743244 0.94 PTGS2 (0.51) PTGS2ALOX5PPARALTB4RLTB4R2
SCHEMBL4454135 0.94 PTGS2 (0.51) PTGS2ALOX5PPARALTB4RLTB4R2
SCHEMBL4446469 0.94 PTGS2 (0.51) PTGS2ALOX5PPARALTB4RLTB4R2
Benzene SCHEMBL11159795 0.92 PPARA (0.51) PTGS2ALOX5PPARALTB4RLTB4R2
SCHEMBL6742752 0.87 PTGS2 (0.45) PTGS2ALOX5PPARALTB4RLTB4R2
SCHEMBL6745914 0.87 LTB4R (0.42) PTGS2ALOX5PPARALTB4RLTB4R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6790914-B2 TRANSPARENT (CROSSLINKED) RESIN FILM CAN BE USED AS A POLARIZING FILM, SURFACE PROTECTIVE FILM, RETARDATION FILM, TRANSPARENT CONDUCTIVE FILM, LIGHT DIFFUSION FILM, FILM FOR AN EL DISPLAY DEVICE, TRANSPARENT CONDUCTIVE COMPOSITE MATERIAL, JSR CORPORATION (JP) 2004-09-14 US disclosed
US-20040106740-A1 Resin film and applications thereof JSR CORPORATION (JP) 2004-06-03 US disclosed
EP-1195397-B1 Composition of cyclic olefin addition copolymer and cross-linked material JSR CORP (JP) 2004-04-14 EP disclosed
US-20020042461-A1 Composition of cyclic olefin addition copolymer and cross-linked material JSR CORPORATION (JP) 2002-04-11 US disclosed
EP-1195397-A1 Composition of cyclic olefin addition copolymer and cross-linked material JSR Corporation (JP) 2002-04-10 EP disclosed