SCHEMBL6742907

SCHEMBL6742907

C1CCC(N2CCNCCNCC2(C2CCCCC2)C2CCCCC2)CC1

nearest known ligand 0.44

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.34
RAD52 P43351 1/20 0.30
HRH3 Q9Y5N1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27360287 0.73 SOS1 (0.46) RAD52
SCHEMBL27971606 0.73 HTR6 (0.37) HTR6
Water SCHEMBL28191062 0.71 HTR6 (0.36) HTR6
SCHEMBL28020820 0.71 HTR6 (0.38) HTR6
SCHEMBL2800752 0.67 SOS1 (0.34) HTR6
SCHEMBL30279570 0.67 HTR6 (0.33) HTR6
SCHEMBL8695162 0.66 HTR6 (0.61) HTR6RAD52HRH3
Piperazine SCHEMBL27903046 0.66 HTR6 (0.61) HTR6RAD52HRH3
SCHEMBL28809524 0.66 HTR6 (0.61) HTR6RAD52HRH3
SCHEMBL451992 0.64 HTR6 (0.64) HTR6RAD52HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6689919-B1 SOLUBLE POLY(OXYFLUOROPHENYLENE) COMPOUNDS WITH EXCELLENT HEAT RESISTANCE, MEMBRANE-FORMABILITY AND CHEMICAL STABILITY JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2004-02-10 US disclosed