Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL535436 | 0.85 | — | — | |
| SCHEMBL192417 | 0.74 | KDM4E (0.31) | LMNA | |
| SCHEMBL6741096 | 0.72 | — | — | |
| SCHEMBL16910904 | 0.71 | ADORA2A (0.32) | ADORA2AADORA2B | |
| SCHEMBL3675830 | 0.71 | — | — | |
| SCHEMBL217424 | 0.67 | — | — | |
| SCHEMBL535386 | 0.67 | — | — | |
| SCHEMBL535541 | 0.65 | IDH1 (0.30) | — | |
| SCHEMBL15417666 | 0.64 | LMNA (0.43) | LMNA | |
| SCHEMBL538163 | 0.62 | LMNA (0.44) | LMNAADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103180316-A | Compounds that modulate intracellular calcium | CALCIMEDICA INC | 2013-06-26 | — | — | CN | disclosed |
| US-20040023805-A1 | Substituted phenyluracils | ANDREE ROLAND (DE) | 2004-02-05 | — | — | US | disclosed |
| US-6649760-B2 | Herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2003-11-18 | — | — | US | disclosed |
| CN-1420873-A | Substituted phenyluracils | BAYER AG (DE) | 2003-05-28 | — | — | CN | disclosed |
| EP-1272478-A1 | SUBSTITUTED PHENYLURACILS | Bayer Aktiengesellschaft (DE) | 2003-01-08 | — | — | EP | disclosed |
| US-20020173425-A1 | Substituted phenyluracils | BAYER AKTIENGESELLSCHAFT (DE) | 2002-11-21 | — | — | US | disclosed |
| WO-2001077084-A1 | SUBSTITUTED PHENYLURACILS | BAYER CROPSCIENCE AG (DE) | 2001-10-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020173425-A1 | Substituted phenyluracils | DPYD, POP1, G6PD | LMNA 4406/4885ADORA2A 2147/4885ADORA2B 2626/4885 |
| US-20040023805-A1 | Substituted phenyluracils | DPYD, POP1, G6PD | LMNA 4406/4885ADORA2A 2147/4885ADORA2B 2626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.