Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6075317 | 0.98 | HTT (0.50) | HTTPTGS1PTGS2TLR8TLR7 | |
| SCHEMBL10650771 | 0.81 | SMN1; SMN2 (0.46) | HTTPTGS1PTGS2TLR8TLR7 | |
| SCHEMBL10654233 | 0.81 | PDPK1 (0.40) | HTTPTGS1PTGS2TLR8TLR7 | |
| Hydrochloric Acid SCHEMBL6074699 | 0.78 | PTGS1 (0.57) | PTGS1PTGS2TLR8TLR7SMN1; SMN2 | |
| SCHEMBL10334317 | 0.77 | HTT (0.58) | HTTPDPK1ALDH1A1SMN1; SMN2HSD17B10 | |
| Hydrochloric Acid SCHEMBL6079172 | 0.77 | TLR8 (0.44) | HTTPTGS1PTGS2TLR8TLR7 | |
| Hydrochloric Acid SCHEMBL10654208 | 0.75 | HTT (0.56) | HTTPDPK1ALDH1A1SMN1; SMN2HSD17B10 | |
| Hydrochloric Acid SCHEMBL6074710 | 0.75 | PTGS1 (0.63) | PTGS1PTGS2TLR8TLR7ALDH1A1 | |
| SCHEMBL6746578 | 0.72 | PTGS1 (0.60) | HTTPTGS1PTGS2ALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL6075219 | 0.71 | PTGS1 (0.58) | HTTPTGS1PTGS2ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689777-B2 | DEPOLYMERIZING HEMOZOIN USING 2-IMINO-NAPHTHO(1,2-D)THIAZOL-5-OL DERIVATIVES | KENNETH S. WARREN INSTITUTE | 2004-02-10 | — | — | US | disclosed |
| US-20030186993-A1 | Anti-malarial compounds, compositions and methods | KENNETH S. WARREN INSTITUTE | 2003-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030186993-A1 | Anti-malarial compounds, compositions and methods | TYR, CRYZ, RHOT2 | HTT 282/4885PTGS1 1815/4885PTGS2 1247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.