Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PHGDH | O43175 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24541593 | 0.91 | CHRM2 (0.33) | SIGMAR1CHRM2CHRM1TSHRTP53 | |
| SCHEMBL26818871 | 0.83 | HRH3 (0.36) | TSHRTP53HRH3 | |
| SCHEMBL23759873 | 0.83 | L3MBTL3 (0.37) | CHRM2CHRM1TSHRTP53HRH3 | |
| SCHEMBL26022672 | 0.83 | L3MBTL3 (0.46) | — | |
| SCHEMBL19119393 | 0.83 | L3MBTL3 (0.46) | — | |
| SCHEMBL10092689 | 0.82 | HRH3 (0.50) | SIGMAR1CHRM2CHRM1TSHRTP53 | |
| SCHEMBL8186259 | 0.80 | HRH3 (0.53) | SIGMAR1CHRM2CHRM1TSHRTP53 | |
| SCHEMBL12858869 | 0.80 | HRH3 (0.53) | SIGMAR1CHRM2CHRM1TSHRTP53 | |
| SCHEMBL6743387 | 0.80 | SIGMAR1 (0.46) | SIGMAR1CHRM2CHRM1TSHRTP53 | |
| SCHEMBL19089531 | 0.79 | L3MBTL3 (0.37) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019178510-A1 | TRIAZACYCLODODECANSULFONAMIDE (\"TCD\")-BASED PROTEIN SECRETION INHIBITORS | KEZAR LIFE SCIENCES (US) | 2019-09-19 | — | — | WO | disclosed |