Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 2/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4820254 | 0.88 | MAPT (0.48) | CCR4KDM4ETDP1TSHR | |
| SCHEMBL14027623 | 0.87 | GAA (0.47) | CCR4KDM4ETDP1TSHR | |
| SCHEMBL4902897 | 0.84 | TSHR (0.39) | KDM4ETDP1TSHRMC4R | |
| SCHEMBL14027639 | 0.81 | MAPT (0.46) | CCR4KDM4ETDP1TRPV6TSHR | |
| SCHEMBL4824654 | 0.79 | KDM4E (0.44) | CCR4KDM4ETDP1HRH3OPRK1 | |
| SCHEMBL6746817 | 0.79 | KDM4E (0.57) | KDM4ETDP1TRPV6TSHR | |
| SCHEMBL14027596 | 0.73 | TRPV6 (0.54) | KDM4ETDP1TRPV6TSHR | |
| SCHEMBL14027221 | 0.73 | TRPV6 (0.54) | KDM4ETDP1TRPV6TSHR | |
| SCHEMBL4913342 | 0.73 | ACP1 (0.44) | KDM4ETSHRHRH3MC4R | |
| SCHEMBL6745111 | 0.73 | GAA (0.44) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699873-B1 | EATING DISORDERS | MILLENNIUM PHARMACEUTICALS, INC. | 2004-03-02 | — | — | US | disclosed |