Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.58 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3423701 | 0.85 | SLC6A3 (0.66) | SLC6A4SLC6A3SLC6A2HTR1AHTR6 | |
| SCHEMBL8107623 | 0.73 | SLC6A2 (0.57) | SLC6A4SLC6A3SLC6A2HTR1AHTR6 | |
| SCHEMBL8207336 | 0.73 | SLC6A4 (0.71) | SLC6A4SLC6A3SLC6A2HTR1AHTR6 | |
| SCHEMBL5829586 | 0.72 | SLC6A4 (0.69) | SLC6A4SLC6A3SLC6A2HTR6NOS3 | |
| SCHEMBL5829683 | 0.72 | SLC6A4 (0.69) | SLC6A4SLC6A3SLC6A2HTR1AHTR6 | |
| SCHEMBL1020817 | 0.72 | SLC6A2 (0.69) | SLC6A4SLC6A3SLC6A2HTR1AHTR6 | |
| SCHEMBL1020818 | 0.72 | SLC6A2 (0.69) | SLC6A4SLC6A3SLC6A2HTR1AHTR6 | |
| SCHEMBL7806031 | 0.71 | SLC6A4 (0.80) | SLC6A4SLC6A3SLC6A2HTR6 | |
| SCHEMBL2889995 | 0.71 | SLC6A4 (0.63) | SLC6A4SLC6A3SLC6A2HTR1AHTR6 | |
| SCHEMBL2889993 | 0.71 | SLC6A4 (0.63) | SLC6A4SLC6A3SLC6A2HTR1AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699873-B1 | EATING DISORDERS | MILLENNIUM PHARMACEUTICALS, INC. | 2004-03-02 | — | — | US | disclosed |