SCHEMBL6744016

SCHEMBL6744016

O=C(OCCl)C(C(F)(F)F)C(F)(F)F

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL618224 0.78 HTT (0.33) HTT
SCHEMBL28575211 0.76 HTT (0.32) HTT
SCHEMBL26339936 0.75 HTT (0.62) HTT
SCHEMBL14715925 0.75 ALDH1A1 (0.43) HTT
SCHEMBL15094074 0.74 HTT (0.32) HTT
SCHEMBL22118453 0.73 HTT (0.35) HTT
SCHEMBL12987661 0.70
SCHEMBL10624881 0.70 HTT (0.30) HTT
SCHEMBL10627346 0.70 MEN1 (0.33) HTT
SCHEMBL12986645 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4766238-A Fluorine-containing compounds, and their preparation and use DAIKIN INDUSTRIES, LTD. (JP) 1988-08-23 US claimed
US-4739123-A Fluorine-containing compounds, and their preparation and use DAIKEN INDUSTRIES, LTD. (JP) 1988-04-19 US claimed
JP-62096436-A None JP disclosed
JP-62096450-A None JP disclosed
US-6703533-B1 MANUFACTURE OF CERTAIN FLUOROCARBONS WHICH HAVE AN OLEFINIC BOND BY DEFLUORINATION OF A FLUOROCARBON STARTING MATERIAL HAVING A CORRESPONDING SATURATED BOND. E. I. DU PONT DE NEMOURS AND COMPANY 2004-03-09 US disclosed
EP-1175380-B1 PREPARATION OF SELECTED FLUOROOLEFINS DU PONT (US) 2003-12-10 EP disclosed
EP-1175380-A1 PREPARATION OF SELECTED FLUOROOLEFINS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2002-01-30 EP disclosed
WO-2001014294-A1 PREPARATION OF SELECTED FLUOROOLEFINS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2001-03-01 WO disclosed
US-4766238-A Fluorine-containing compounds, and their preparation and use DAIKIN INDUSTRIES, LTD. (JP) 1988-08-23 US disclosed
US-4739123-A Fluorine-containing compounds, and their preparation and use DAIKEN INDUSTRIES, LTD. (JP) 1988-04-19 US disclosed
JP-S6296450-A NOVEL FLUORINE-CONTAINING COMPOUND AND PRODUCTION THEREOF DAIKIN IND LTD 1987-05-02 JP disclosed
JP-S6296436-A PRODUCTION OF 2-TRIFLUOROMETHYL-3,3,3-TRIFLUOROPROPENE DAIKIN IND LTD 1987-05-02 JP disclosed