SCHEMBL6744116

SCHEMBL6744116

OC1C=CC=C(c2ccncn2)C1O

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.31
CYP2D6 P10635 1/20 0.30
CAMKK2 Q96RR4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6744628 0.78 KDM4E (0.43) HSP90AA1
SCHEMBL30595872 0.66 HSP90AA1 (0.52) HSP90AA1CYP2D6
SCHEMBL2814353 0.66 HSP90AA1 (0.52) HSP90AA1CYP2D6
SCHEMBL6740748 0.65 CYP2A6 (0.39)
SCHEMBL6741707 0.65 AR (0.42) CYP2D6
SCHEMBL13910999 0.64 HSP90AA1 (0.50) HSP90AA1CYP2D6
SCHEMBL639798 0.63 ALDH1A1 (0.32)
SCHEMBL639799 0.63 ALDH1A1 (0.32)
SCHEMBL639800 0.63 ALDH1A1 (0.32)
SCHEMBL24252409 0.62 CCNT1 (0.33) CAMKK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040086983-A1 Method for producing a heterocyclic compound and an aromatic carboxylic acid having one or more hydroxyl groups, and modified aromatic ring dioxygenase MARINE BIOTHECHNOLOGY INSTITUTE., LTD. (JP) 2004-05-06 US disclosed