Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL16332561 | 1.00 | ALDH1A1 (0.45) | ALDH1A1ALOX15MAOAMAPTKDM4E | |
| Bromide SCHEMBL6739425 | 1.00 | ALDH1A1 (0.45) | ALDH1A1ALOX15MAOAMAPTKDM4E | |
| Bromide SCHEMBL7687601 | 1.00 | ALDH1A1 (0.45) | ALDH1A1ALOX15MAOAMAPTKDM4E | |
| Bromide SCHEMBL16333039 | 1.00 | ALDH1A1 (0.45) | ALDH1A1ALOX15MAOAMAPTKDM4E | |
| SCHEMBL9336430 | 0.97 | ALDH1A1 (0.47) | ALDH1A1ALOX15MAOAMAPTKDM4E | |
| SCHEMBL123127 | 0.97 | ALDH1A1 (0.47) | ALDH1A1ALOX15MAOAMAPTKDM4E | |
| Water SCHEMBL4753900 | 0.94 | ALDH1A1 (0.45) | ALDH1A1ALOX15MAOAMAPTKDM4E | |
| SCHEMBL309527 | 0.94 | ALDH1A1 (0.45) | ALDH1A1ALOX15MAOAMAPTKDM4E | |
| Iodide SCHEMBL2127044 | 0.94 | ALDH1A1 (0.45) | ALDH1A1ALOX15MAOAMAPTKDM4E | |
| SCHEMBL9413781 | 0.94 | ALDH1A1 (0.45) | ALDH1A1ALOX15MAOAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023242061-A1 | SYNTHESIS OF A CATALYST COMPRISING A HIGH-PURITY NU-86 ZEOLITE AND IRON FOR THE CONVERSON OF NOX AND N2O | IFP Energies Nouvelles (FR) | 2023-12-21 | — | — | WO | claimed |
| WO-2023242061-A1 | SYNTHESIS OF A CATALYST COMPRISING A HIGH-PURITY NU-86 ZEOLITE AND IRON FOR THE CONVERSON OF NOX AND N2O | IFP Energies Nouvelles (FR) | 2023-12-21 | — | — | WO | disclosed |
| WO-2023242061-A1 | SYNTHESIS OF A CATALYST COMPRISING A HIGH-PURITY NU-86 ZEOLITE AND IRON FOR THE CONVERSON OF NOX AND N2O | IFP Energies Nouvelles (FR) | 2023-12-21 | — | — | WO | disclosed |
| US-6692723-B2 | MTT zeolite comprising crystals and crystal aggregates with specific granulometries, and its use as a catalyst for isomerizing straight chain paraffins | INSTITUT FRANCAIS DU PETROLE (FR) | 2004-02-17 | — | — | US | disclosed |
| US-6548040-B1 | Isomerization catalyst for hydrocarbons | INSTITUT FRANCAIS DU PETROLE (FR) | 2003-04-15 | — | — | US | disclosed |
| US-20020192156-A1 | MTT zeolite comprising crystals and crystal aggregates with specific granulometries, and its use as a catalyst for isomerising straight chain paraffins | INSTITUT FRANCAIS DU PETROLE (FR) | 2002-12-19 | — | — | US | disclosed |
| US-6475464-B1 | Process for preparing a zeolite with structure type MTT using zeolitic material seeds | INSTITUT FRANCAIS DU PETROLE (FR) | 2002-11-05 | — | — | US | disclosed |
| EP-0377291-B1 | Zeolites | ICI PLC (GB) | 1995-10-25 | — | — | EP | disclosed |
| US-5102641-A | ZEOLITE NU-87 | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-04-07 | — | — | US | disclosed |
| EP-0377291-A1 | Zeolites | INSTITUT FRANCAIS DU PETROLE (FR) | 1990-07-11 | — | — | EP | disclosed |