Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 7/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.40 |
| ▸ | RXRA | P19793 | 2/20 | 0.39 |
| ▸ | RXRB | P28702 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6164836 | 0.84 | SUCNR1 (0.46) | FFAR4FFAR1PTGER4MAOB | |
| SCHEMBL6744828 | 0.80 | MAOB (0.40) | MAOBCYP2C9KMT2AADORA3NPC1 | |
| SCHEMBL6740849 | 0.79 | MAOB (0.47) | FFAR4FFAR1MAOBHTTNPC1 | |
| SCHEMBL6163345 | 0.79 | CA12 (0.46) | FFAR4FFAR1MAOBKMT2ANPC1 | |
| SCHEMBL6164397 | 0.77 | PTPN1 (0.50) | FFAR4FFAR1MAOBALDH1A1 | |
| SCHEMBL6162827 | 0.77 | MAOB (0.43) | FFAR4FFAR1MAOBCYP2C9HTT | |
| SCHEMBL6166638 | 0.76 | ACLY (0.44) | FFAR4FFAR1MAOB | |
| SCHEMBL6162225 | 0.76 | MGLL (0.41) | FFAR4FFAR1MAOBCYP2C9KMT2A | |
| SCHEMBL5395877 | 0.76 | FFAR1 (0.62) | FFAR1MAOBNPC1RAB9A | |
| SCHEMBL6622607 | 0.76 | HCAR2 (0.47) | FFAR4FFAR1MAOBKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6693098-B2 | CARBOXYLIC ACID OR TETRAZOLE DERIVATIVES CONTAINING CARBAMATE GROUPS ARE USEFUL FOR TREATING THE CONDITIONS ASSOCIATED WITH THE URINARY TRACT, PAIN, INFLAMMATION, RESPIRATORY STATES, EDEMA FORMATION OF HYPOTENSIVE VASCULAR DISEASES | SYNTEX (U.S.A) LLC | 2004-02-17 | — | — | US | claimed |