SCHEMBL6744912

SCHEMBL6744912

Cc1cccc([N+](C)(C)C)c1C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.47
TRPA1 O75762 2/20 0.44
ATM Q13315 1/20 0.44
CYP2A6 P11509 2/20 0.39
CYP1A2 P05177 1/20 0.39
TSHR P16473 3/20 0.38
ALDH1A1 P00352 3/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
MAPT P10636 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
KEAP1 Q14145 1/20 0.34
NFE2L2 Q16236 1/20 0.34
CD44 P16070 1/20 0.33
RAPGEF4 Q8WZA2 1/20 0.33
HTR2C P28335 1/20 0.32
ADRB1 P08588 1/20 0.32
AHR P35869 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7763343 0.78 ACHE (0.50) ACHECYP2A6CYP1A2TSHRALDH1A1
Hydrogen Sulfide SCHEMBL28219896 0.76 TRPA1 (0.58) ACHETRPA1ATMCYP2A6CYP1A2
Water SCHEMBL5327527 0.76 ACHE (0.47) ACHECYP2A6CYP1A2TSHRALDH1A1
Hydrochloric Acid SCHEMBL28427471 0.76 ACHE (0.47) ACHECYP2A6CYP1A2TSHRALDH1A1
Iodide SCHEMBL11777950 0.76 ACHE (0.47) ACHECYP2A6CYP1A2TSHRALDH1A1
Bromide SCHEMBL8612061 0.76 ACHE (0.47) ACHECYP2A6CYP1A2TSHRALDH1A1
Hydrochloric Acid SCHEMBL11860221 0.76 ACHE (0.47) ACHECYP2A6CYP1A2TSHRALDH1A1
Hydrochloric Acid SCHEMBL10756381 0.75 CYP3A4 (0.59) ACHETSHRALDH1A1MAPTSMN1; SMN2
Hydrochloric Acid SCHEMBL27734632 0.74 ACHE (0.43) ACHECYP2A6CYP1A2TSHR
SCHEMBL40704 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160374348-A1 POLYMER-SUPPORTED ANTIMICROBIAL COMPOSITES AND METHODS OF USING THE SAME DERINGER-NEY INC (US) 2016-12-29 US claimed
US-6689485-B2 Powerful reductant for decontamination of groundwater and surface streams THE PENN STATE RESEARCH FOUNDATION 2004-02-10 US claimed
US-20020006867-A1 Powerful reductant for decontamination of groundwater and surface streams THE PENN STATE RESEARCH FOUNDATION 2002-01-17 US claimed
EP-0141371-B1 SECONDARY BATTERY SHOWA DENKO KABUSHIKI KAISHA (JP) 1988-08-10 EP claimed
US-20160374348-A1 POLYMER-SUPPORTED ANTIMICROBIAL COMPOSITES AND METHODS OF USING THE SAME DERINGER-NEY INC (US) 2016-12-29 US disclosed
US-6689485-B2 Powerful reductant for decontamination of groundwater and surface streams THE PENN STATE RESEARCH FOUNDATION 2004-02-10 US disclosed
US-20020006867-A1 Powerful reductant for decontamination of groundwater and surface streams THE PENN STATE RESEARCH FOUNDATION 2002-01-17 US disclosed
EP-0971962-A1 CATALYST SYSTEM FOR HIGH YIELD SYNTHESIS OF POLYOLEFINS THE DOW CHEMICAL COMPANY (US) 2000-01-19 EP disclosed
WO-1998045337-A1 CATALYST SYSTEM FOR HIGH YIELD SYNTHESIS OF POLYOLEFINS THE DOW CHEMICAL COMPANY (US) 1998-10-15 WO disclosed
CN-1009042-B SECONDARY CELL SHOWA DENKO KK (JP) 1990-08-01 CN disclosed
EP-0141371-B1 SECONDARY BATTERY SHOWA DENKO KABUSHIKI KAISHA (JP) 1988-08-10 EP disclosed
CN-85103100-A SECONDARY CELL 1987-08-19 CN disclosed
US-4537843-A ELECTRODES OF POLYMER WITH CONJUGATED DOUBLE BONDS IN MAIN CHAIN, SHOWA DENKO KABUSHIKI KAISHA (JP) 1985-08-27 US disclosed
EP-0141371-A1 Secondary Battery SHOWA DENKO KABUSHIKI KAISHA (JP) 1985-05-15 EP disclosed