Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 7/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4825382 | 0.80 | MC4R (0.38) | SMN1; SMN2MC4RTSHRLMNA | |
| SCHEMBL6745107 | 0.78 | TRIM58 (0.40) | TACR1MC4RTSHR | |
| SCHEMBL4555811 | 0.76 | CHEK2 (0.45) | TACR1MC4R | |
| SCHEMBL4823017 | 0.76 | MAPT (0.46) | SMN1; SMN2MC4RMAPT | |
| Formic Acid SCHEMBL4819224 | 0.76 | TSHR (0.36) | TACR1SMN1; SMN2MC4RKCNH2TSHR | |
| Formic Acid SCHEMBL4819237 | 0.74 | MC4R (0.39) | TACR1SMN1; SMN2MC4RTSHR | |
| SCHEMBL4819232 | 0.74 | MC4R (0.39) | TACR1SMN1; SMN2MC4RKCNH2TSHR | |
| SCHEMBL4816428 | 0.74 | MAPT (0.46) | SMN1; SMN2TSHRMAPT | |
| SCHEMBL4369319 | 0.72 | GAA (0.43) | SMN1; SMN2TSHRMAPT | |
| SCHEMBL6745111 | 0.72 | GAA (0.44) | SMN1; SMN2TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699873-B1 | EATING DISORDERS | MILLENNIUM PHARMACEUTICALS, INC. | 2004-03-02 | — | — | US | disclosed |