Sugi Predict

Sugi Predict / Compounds / SCHEMBL6745447

SCHEMBL6745447

SCHEMBL6745447

CCO[Si](OCC)(OCC)c1ccc(N(c2ccccc2)c2ccc(-c3ccc(N(c4ccccc4)c4ccccc4)cc3)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.38
▸ L3MBTL1 Q9Y468 2/20 0.38
▸ KDM4E B2RXH2 2/20 0.38
▸ MAPT P10636 2/20 0.38
▸ CYP1A2 P05177 1/20 0.38
▸ CYP3A4 P08684 1/20 0.38
▸ CYP2D6 P10635 1/20 0.38
▸ CYP2C9 P11712 1/20 0.38
▸ CYP2C19 P33261 1/20 0.38
▸ TDP1 Q9NUW8 1/20 0.38
▸ NPC1 O15118 2/20 0.33
▸ RAB9A P51151 2/20 0.33
▸ MEN1 O00255 2/20 0.33
▸ KMT2A Q03164 2/20 0.33
▸ FAAH O00519 1/20 0.33
▸ MGLL Q99685 1/20 0.33
▸ CRHBP P24387 1/20 0.33
▸ ATM Q13315 1/20 0.33
▸ CRHR2 Q13324 1/20 0.33
▸ TLR9 Q9NR96 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12615158 1.00 ALDH1A1 (0.38) ALDH1A1L3MBTL1KDM4EMAPTCYP1A2
SCHEMBL1797243 0.95 ALDH1A1 (0.42) ALDH1A1L3MBTL1KDM4EMAPTCYP1A2
SCHEMBL6748331 0.95 ALDH1A1 (0.42) ALDH1A1L3MBTL1KDM4EMAPTCYP1A2
SCHEMBL6748607 0.94 CYP2C19 (0.37) ALDH1A1L3MBTL1KDM4EMAPTCYP1A2
SCHEMBL6744724 0.94 CYP2C19 (0.37) ALDH1A1L3MBTL1KDM4EMAPTCYP1A2
SCHEMBL6744754 0.94 CYP2C19 (0.37) ALDH1A1L3MBTL1KDM4EMAPTCYP1A2
SCHEMBL6746686 0.94 CYP2C19 (0.37) ALDH1A1L3MBTL1KDM4EMAPTCYP1A2
SCHEMBL6746689 0.88 ALDH1A1 (0.37) ALDH1A1L3MBTL1KDM4EMAPTCYP1A2
SCHEMBL6750033 0.88 CYP2C19 (0.40) ALDH1A1L3MBTL1KDM4EMAPTCYP1A2
SCHEMBL6745184 0.88 CYP2C19 (0.40) ALDH1A1L3MBTL1KDM4EMAPTCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6696588-B2 OXIDATION POTENTIAL OF .3-1.5 V ON THE BASIS OF A STANDARD HYDROGEN ELECTRODE, ALKOXY AND AROMATIC AMINE DERIVATIVES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-02-24 — — US disclosed
EP-0861845-B1 Silicon-containing compound and organic electroluminescence device using the same SUMITOMO CHEMICAL CO (JP) 2003-05-28 — — EP disclosed
US-20020115877-A1 Silicon-containing compound and organic electroluminescence device using the same SUMITOMO CHEMICAL COMPANY, LIMITED 2002-08-22 — — US disclosed
US-6369258-B1 SILICON COMPOUND WITH OXIDATION POTENTIAL ON HYDROGEN ELECTRODE POTENTIAL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-04-09 — — US disclosed
EP-0861845-A2 Silicon-containing compound and organic electroluminescence device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-09-02 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020115877-A1 Silicon-containing compound and organic electroluminescence device using the same EPCAM, PIEZO1, OR10J3 ALDH1A1 460/4885L3MBTL1 2398/4885KDM4E 296/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.