SCHEMBL6745910

SCHEMBL6745910

CCCc1cccc(OPOc2cccc(CCC)c2CCC)c1CCC

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LTB4R Q15722 7/20 0.41
LTB4R2 Q9NPC1 7/20 0.41
PTGS2 P35354 2/20 0.37
ALOX5 P09917 1/20 0.37
ELANE P08246 2/20 0.36
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
GAA P10253 1/20 0.35
HPGD P15428 1/20 0.35
SLC6A2 P23975 2/20 0.35
SLC6A4 P31645 2/20 0.35
SLC6A3 Q01959 2/20 0.35
HTR1A P08908 2/20 0.34
ADRA2A P08913 2/20 0.34
ADRA2B P18089 2/20 0.34
ADRA2C P18825 2/20 0.34
NISCH Q9Y2I1 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6742752 0.86 PTGS2 (0.45) LTB4RLTB4R2PTGS2ALOX5ELANE
SCHEMBL6745914 0.86 LTB4R (0.42) LTB4RLTB4R2PTGS2ALOX5ELANE
SCHEMBL28541193 0.84 LTB4R (0.44) LTB4RLTB4R2PTGS2ALOX5ELANE
SCHEMBL6743239 0.83 PTGS2 (0.50) LTB4RLTB4R2PTGS2ALOX5
SCHEMBL4446465 0.83 PTGS2 (0.50) LTB4RLTB4R2PTGS2ALOX5
SCHEMBL4454133 0.83 PTGS2 (0.50) LTB4RLTB4R2PTGS2ALOX5
SCHEMBL1965860 0.83 PTGS2 (0.50) LTB4RLTB4R2PTGS2ALOX5
SCHEMBL4443929 0.83 PTGS2 (0.50) LTB4RLTB4R2PTGS2ALOX5
SCHEMBL6745885 0.83 PTGS2 (0.50) LTB4RLTB4R2PTGS2ALOX5
SCHEMBL11260579 0.81 TAAR1 (0.32) LTB4RLTB4R2PTGS2ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6790914-B2 TRANSPARENT (CROSSLINKED) RESIN FILM CAN BE USED AS A POLARIZING FILM, SURFACE PROTECTIVE FILM, RETARDATION FILM, TRANSPARENT CONDUCTIVE FILM, LIGHT DIFFUSION FILM, FILM FOR AN EL DISPLAY DEVICE, TRANSPARENT CONDUCTIVE COMPOSITE MATERIAL, JSR CORPORATION (JP) 2004-09-14 US disclosed
US-20040106740-A1 Resin film and applications thereof JSR CORPORATION (JP) 2004-06-03 US disclosed
EP-1195397-B1 Composition of cyclic olefin addition copolymer and cross-linked material JSR CORP (JP) 2004-04-14 EP disclosed
US-20020042461-A1 Composition of cyclic olefin addition copolymer and cross-linked material JSR CORPORATION (JP) 2002-04-11 US disclosed
EP-1195397-A1 Composition of cyclic olefin addition copolymer and cross-linked material JSR Corporation (JP) 2002-04-10 EP disclosed