Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.39 |
| ▸ | FEN1 | P39748 | 8/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 7/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6746652 | 0.88 | CA1 (0.40) | PTGS2PTGS1FEN1CA1CA2 | |
| SCHEMBL6729023 | 0.86 | PTGS2 (0.43) | PTGS2PTGS1FEN1CYP11B1CYP11B2 | |
| SCHEMBL6743007 | 0.86 | FEN1 (0.41) | PTGS2PTGS1FEN1CA1CA2 | |
| SCHEMBL6744788 | 0.85 | PTGS2 (0.48) | PTGS2PTGS1FEN1CA1CA2 | |
| SCHEMBL6746820 | 0.85 | PTGS2 (0.51) | PTGS2PTGS1FEN1CA1CA2 | |
| SCHEMBL6833662 | 0.84 | PTGS2 (0.43) | PTGS2PTGS1CA1CA2APLNR | |
| SCHEMBL6747196 | 0.84 | CA1 (0.43) | PTGS2PTGS1FEN1CA1CA2 | |
| SCHEMBL6746864 | 0.82 | FEN1 (0.42) | PTGS2PTGS1FEN1CA1CA2 | |
| SCHEMBL6750085 | 0.82 | ALOX5AP (0.39) | PTGS2PTGS1FEN1CA1CA2 | |
| SCHEMBL6838591 | 0.82 | CA1 (0.46) | PTGS2PTGS1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699884-B2 | ANTIINFLAMMATORY CYCLOOXYGENASE INHIBITORS. | PHARMACIA CORPORATION | 2004-03-02 | — | — | US | claimed |
| US-6699884-B2 | ANTIINFLAMMATORY CYCLOOXYGENASE INHIBITORS. | PHARMACIA CORPORATION | 2004-03-02 | — | — | US | disclosed |