Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | ULK1 | O75385 | 3/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.33 |
| ▸ | ULK2 | Q8IYT8 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | ESRRA | P11474 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL675825 | 0.90 | AURKA (0.38) | AURKAKDRAURKBPTPN1HTT | |
| SCHEMBL675453 | 0.86 | AURKA (0.35) | AURKAKDRAURKBHTTAPOBEC3A | |
| SCHEMBL29419084 | 0.85 | PTPN1 (0.37) | PTPN1ULK1PRKAA2PRKAA1ULK2 | |
| SCHEMBL119728 | 0.85 | PTPN1 (0.37) | PTPN1ULK1PRKAA2PRKAA1ULK2 | |
| SCHEMBL676320 | 0.85 | PTPN1 (0.40) | PTPN1ULK1PRKAA2PRKAA1ULK2 | |
| SCHEMBL5942385 | 0.84 | LCK (0.37) | KDRPTPN1ALDH1A1 | |
| SCHEMBL526805 | 0.83 | PTPN1 (0.36) | PTPN1ULK1PRKAA2PRKAA1ULK2 | |
| SCHEMBL29358934 | 0.83 | PTPN1 (0.36) | PTPN1ULK1PRKAA2PRKAA1ULK2 | |
| SCHEMBL676283 | 0.82 | PTPN1 (0.34) | PTPN1ULK1PRKAA2PRKAA1ULK2 | |
| SCHEMBL675856 | 0.82 | PTPN1 (0.35) | AURKAKDRAURKBPTPN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10136643-B2 | Fungicidal composition and method for controlling plant diseases | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2018-11-27 | — | — | US | claimed |
| US-9474281-B2 | Fungicidal composition and method for controlling plant diseases | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2016-10-25 | — | — | US | claimed |
| US-20150164084-A1 | FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2015-06-18 | — | — | US | claimed |
| US-8962661-B2 | Fungicidal composition and method for controlling plant diseases | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2015-02-24 | — | — | US | claimed |
| EP-2323487-A2 | FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2011-05-25 | — | — | EP | claimed |
| US-20110104307-A1 | FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2011-05-05 | — | — | US | claimed |
| WO-2010002026-A2 | FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2010-01-07 | — | — | WO | claimed |
| EP-2036436-A1 | ANTIBACTERIAL COMPOSITION AND METHOD FOR CONTROL OF PLANT DISEASE | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2009-03-18 | — | — | EP | claimed |
| US-20060194849-A1 | Fungicidal composition and method for controlling plant diseases | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2006-08-31 | — | — | US | claimed |
| EP-1679003-A1 | BACTERICIDE COMPOSITION AND METHOD OF CONTROLLING PLANT DISEASE | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2006-07-12 | — | — | EP | claimed |
| US-20060089390-A1 | 3-benzoyl-2,4,5-substituted pyridine derivatives or salts thereof and bactericides containing the same | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2006-04-27 | — | — | US | claimed |
| EP-1559320-A1 | 3-BENZOYL-2,4,5-SUBSTITUTED PYRIDINE DERIVATIVES OR SALTS THEREOF AND BACTERICIDES CONTAINING THE SAME | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2005-08-03 | — | — | EP | claimed |
| US-10136643-B2 | Fungicidal composition and method for controlling plant diseases | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2018-11-27 | — | — | US | disclosed |
| US-20170188579-A1 | FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES | ISHIHARA SANGYO KAISHA (JP) | 2017-07-06 | — | — | US | disclosed |
| US-9655362-B2 | Fungicidal composition and method for controlling plant diseases | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2017-05-23 | — | — | US | disclosed |
| US-20160353737-A1 | FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2016-12-08 | — | — | US | disclosed |
| US-20060194849-A1 | Fungicidal composition and method for controlling plant diseases | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2006-08-31 | — | — | US | disclosed |
| EP-1679003-A1 | BACTERICIDE COMPOSITION AND METHOD OF CONTROLLING PLANT DISEASE | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| US-20060089390-A1 | 3-benzoyl-2,4,5-substituted pyridine derivatives or salts thereof and bactericides containing the same | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2006-04-27 | — | — | US | disclosed |
| EP-1559320-A1 | 3-BENZOYL-2,4,5-SUBSTITUTED PYRIDINE DERIVATIVES OR SALTS THEREOF AND BACTERICIDES CONTAINING THE SAME | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2005-08-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160353737-A1 | FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES | AFF4, HCN4, CNPY2 | AURKA 4661/4885KDR 4690/4885AURKB 4668/4885 |
| US-20150164084-A1 | FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES | AFF4, HCN4, CNPY2 | AURKA 4661/4885KDR 4690/4885AURKB 4668/4885 |
| US-10136643-B2 | Fungicidal composition and method for controlling plant diseases | AFF4, HCN4, CNPY2 | AURKA 4661/4885KDR 4690/4885AURKB 4668/4885 |
| US-20110104307-A1 | FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES | AFF4, HCN4, CNPY2 | AURKA 4661/4885KDR 4690/4885AURKB 4668/4885 |
| US-20060194849-A1 | Fungicidal composition and method for controlling plant diseases | CBR3, CNPY2, PAH | AURKA 4458/4885KDR 2646/4885AURKB 4701/4885 |
| US-20170188579-A1 | FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES | CBR3, CNPY2, PAH | AURKA 4458/4885KDR 2646/4885AURKB 4701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.