Dimethylformamide

Dimethylformamide

SCHEMBL6746432

CN(C)C=O.COCCOCCOCCOC

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.47
CA2 P00918 1/20 0.38
CYP3A4 P08684 1/20 0.33
USP2 O75604 1/20 0.31
ALOX15 P16050 1/20 0.31
PIK3CD O00329 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethylformamide SCHEMBL7942578 1.00 TSHR (0.47) TSHRCA2CYP3A4USP2ALOX15
Dimethylformamide SCHEMBL28253639 1.00 TSHR (0.47) TSHRCA2CYP3A4USP2ALOX15
Dimethylformamide SCHEMBL2530045 0.92 TSHR (0.56) TSHRCA2USP2ALOX15PIK3CD
Dimethylformamide SCHEMBL28261531 0.89 MEN1 (0.46) TSHRCA2USP2ALOX15
Triethylene Glycol SCHEMBL9487295 0.89 MEN1 (0.46) TSHRCA2USP2ALOX15
Dimethylformamide SCHEMBL14813149 0.82 TSHR (0.45) TSHRUSP2ALOX15
Dimethylformamide SCHEMBL4939650 0.80 TSHR (0.43) TSHRUSP2ALOX15
Dimethylformamide SCHEMBL10802383 0.79 TSHR (0.47) TSHRCYP3A4ALOX15
SCHEMBL8745522 0.78 CA2 (0.34) CA2
SCHEMBL28102916 0.78 CA2 (0.34) TSHRCA2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1490390-A2 C-17 SPIROLACTONIZATION AND 6,7 OXIDATION OF STEROIDS Pharmacia Corporation (US) 2004-12-29 EP claimed
US-20040024202-A1 C-17 spirolactonization and 6,7 oxidation of steroids PHARMACIA CORPORATION 2004-02-05 US claimed
WO-2003082894-A2 C-17 SPIROLACTONIZATION AND 6,7 OXIDATION OF STEROIDS PHARMACIA CORPORATION (US) 2003-10-09 WO claimed
CN-110392724-A Mixture containing perovskite compound 住友化学株式会社 2019-10-29 CN disclosed
CN-109275335-B The manufacturing method of composition and composition 住友化学株式会社 2019-10-15 CN disclosed
CN-110114441-A Composition, film, laminate structure, light emitting device and display 住友化学株式会社 2019-08-09 CN disclosed
CN-110088229-A Composition comprising a metal oxide and a metal oxide 住友化学株式会社 2019-08-02 CN disclosed
CN-110088230-A COMPOSITION, FILM, LAMINATED STRUCTURE, LIGHT-EMITTING DEVICE, DISPLAY, AND METHOD FOR PRODUCING COMPOSITION 住友化学株式会社 2019-08-02 CN disclosed
CN-110088231-A Composition, film, laminate structure, light emitting device and display 住友化学株式会社 2019-08-02 CN disclosed
CN-110088232-A Composition, film, laminate structure, light emitting device and display 住友化学株式会社 2019-08-02 CN disclosed
CN-109328178-A Composition comprising a metal oxide and a metal oxide 住友化学株式会社 2019-02-12 CN disclosed
CN-109311691-A Compound, dispersion composition, and resin composition 住友化学株式会社 2019-02-05 CN disclosed
CN-109311692-A Composition and compound 住友化学株式会社 2019-02-05 CN disclosed
CN-109275335-A The manufacturing method of composition and composition 住友化学株式会社 2019-01-25 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040024202-A1 C-17 spirolactonization and 6,7 oxidation of steroids HSD17B7, NR3C2, HSD17B13 TSHR 2395/4885CA2 1896/4885CYP3A4 118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.