Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.54 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Caprolactam SCHEMBL28170207 | 0.87 | TSHR (0.45) | TSHRFKBP5CRBNOR51E2ALDH1A1 | |
| Caprolactam SCHEMBL28358108 | 0.85 | TSHR (0.58) | TSHRFKBP5CRBNOR51E2ALDH1A1 | |
| Styrene SCHEMBL28119515 | 0.81 | TSHR (0.43) | TSHRFKBP5CRBNOR51E2ALDH1A1 | |
| Caprolactam SCHEMBL11276986 | 0.80 | CRBN (0.53) | FKBP5CRBNOR51E2KDM4EGAA | |
| Caprolactam SCHEMBL6747086 | 0.80 | FKBP5 (0.46) | TSHRFKBP5CRBNOR51E2ALDH1A1 | |
| Cyclopropane SCHEMBL11750295 | 0.79 | TSHR (0.86) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL660331 | 0.79 | TSHR (0.86) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| Caprolactam SCHEMBL28309060 | 0.79 | CRBN (0.52) | TSHRFKBP5CRBNOR51E2KDM4E | |
| 2-Pyrrolidone SCHEMBL27468084 | 0.78 | OR51E2 (0.41) | TSHRFKBP5CRBNOR51E2ALDH1A1 | |
| Acrylic Acid Ethyl Ester SCHEMBL2492791 | 0.78 | OR51E2 (0.47) | TSHRFKBP5CRBNOR51E2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699544-B2 | Self-reinforced shaped article | ROEHM GMBH & CO. KG (DE) | 2004-03-02 | — | — | US | disclosed |
| US-20030017289-A1 | Self-reinforcing thermoplastically-deformable semi-finished product, in particular for the production of sanitary items, method for production thereof and moulded bodies made therefrom | ROEHM GMBH & CO. KG (DE) | 2003-01-23 | — | — | US | disclosed |