Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP5 | Q13451 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.31 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.31 |
| ▸ | MERTK | Q12866 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Pyrrolidone SCHEMBL17241782 | 0.94 | OR51E2 (0.46) | FKBP5CRBNOR51E2THRBTSHR | |
| Caprolactam SCHEMBL28037719 | 0.87 | FKBP5 (0.47) | FKBP5CRBNOR51E2THRBTSHR | |
| Caprolactam SCHEMBL6408803 | 0.85 | FKBP5 (0.42) | FKBP5CRBNOR51E2THRBTSHR | |
| Caprolactam SCHEMBL27989255 | 0.84 | L3MBTL1 (0.35) | FKBP5CRBNTHRBKDM4EPOLB | |
| Caprolactam SCHEMBL5610881 | 0.83 | FKBP5 (0.40) | FKBP5CRBNOR51E2THRBTSHR | |
| 2-Pyrrolidone SCHEMBL28304483 | 0.82 | OR51E2 (0.46) | FKBP5CRBNOR51E2THRBTSHR | |
| Caprolactam SCHEMBL28170750 | 0.82 | CRBN (0.52) | FKBP5CRBNOR51E2TSHRKDM4E | |
| Caprolactam SCHEMBL2036759 | 0.82 | FKBP5 (0.39) | FKBP5CRBNOR51E2THRBTSHR | |
| 2-Pyrrolidone SCHEMBL8133376 | 0.81 | OR51E2 (0.47) | FKBP5CRBNOR51E2THRBTSHR | |
| Caprolactam SCHEMBL6746702 | 0.80 | TSHR (0.54) | FKBP5CRBNOR51E2THRBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699544-B2 | Self-reinforced shaped article | ROEHM GMBH & CO. KG (DE) | 2004-03-02 | — | — | US | disclosed |
| US-20030017289-A1 | Self-reinforcing thermoplastically-deformable semi-finished product, in particular for the production of sanitary items, method for production thereof and moulded bodies made therefrom | ROEHM GMBH & CO. KG (DE) | 2003-01-23 | — | — | US | disclosed |