Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316409 | 0.82 | IDO1 (0.46) | CYP1A2TAAR1HTTATMMEN1 | |
| SCHEMBL21104761 | 0.82 | HPGD (0.53) | HTTCHRM2HPGDATMMEN1 | |
| SCHEMBL11372205 | 0.79 | CHRM2 (0.44) | CYP1A2CYP2A6TAAR1HTTCHRM2 | |
| SCHEMBL8040670 | 0.79 | CHRM2 (0.47) | HTTCHRM2HPGDATMMEN1 | |
| SCHEMBL16741453 | 0.78 | LOXL2 (0.45) | HTTALDH1A1L3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL15013073 | 0.75 | KMT2A (0.47) | HTTCHRM2HPGDATMMEN1 | |
| SCHEMBL23838693 | 0.74 | ADRB2 (0.54) | CYP1A2HTTHPGDMAPTKDM4E | |
| SCHEMBL15961521 | 0.73 | MEN1 (0.44) | HTTCHRM2HPGDATMMEN1 | |
| SCHEMBL6745878 | 0.73 | MC5R (0.54) | CYP1A2CYP2A6MAPK1CA12CA1 | |
| SCHEMBL21058227 | 0.73 | ATM (0.48) | CYP1A2HTTHPGDATMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699873-B1 | EATING DISORDERS | MILLENNIUM PHARMACEUTICALS, INC. | 2004-03-02 | — | — | US | disclosed |