Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP5 | Q13451 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 5/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Pyrrolidone SCHEMBL12468588 | 0.94 | OR51E2 (0.46) | FKBP5CRBNOR51E2KDM4EGAA | |
| Caprolactam SCHEMBL28170750 | 0.82 | CRBN (0.52) | FKBP5CRBNOR51E2KDM4EGAA | |
| Caprolactam SCHEMBL2036757 | 0.82 | FKBP5 (0.39) | FKBP5CRBNOR51E2KDM4EGAA | |
| 2-Pyrrolidone SCHEMBL28304484 | 0.81 | OR51E2 (0.44) | FKBP5CRBNOR51E2KDM4EGAA | |
| Caprolactam SCHEMBL6746700 | 0.80 | FKBP5 (0.46) | FKBP5CRBNOR51E2KDM4EGAA | |
| Cyclohexane SCHEMBL4358222 | 0.79 | TSHR (0.43) | TSHR | |
| 2-Pyrrolidone SCHEMBL28096599 | 0.79 | OR51E2 (0.42) | FKBP5CRBNOR51E2 | |
| SCHEMBL5604495 | 0.79 | TSHR (0.35) | TSHR | |
| Caprolactam SCHEMBL28037719 | 0.78 | FKBP5 (0.47) | FKBP5CRBNOR51E2KDM4EGAA | |
| Caprolactam SCHEMBL4163313 | 0.78 | CRBN (0.59) | FKBP5CRBNOR51E2KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699544-B2 | Self-reinforced shaped article | ROEHM GMBH & CO. KG (DE) | 2004-03-02 | — | — | US | disclosed |
| US-20030017289-A1 | Self-reinforcing thermoplastically-deformable semi-finished product, in particular for the production of sanitary items, method for production thereof and moulded bodies made therefrom | ROEHM GMBH & CO. KG (DE) | 2003-01-23 | — | — | US | disclosed |