Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 5/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FHIT | P49789 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL522560 | 0.79 | TSHR (0.44) | CHRNB2CHRNA4EPHX2CHRNB4CHRNA3 | |
| SCHEMBL524490 | 0.79 | TSHR (0.44) | CHRNB2CHRNA4EPHX2CHRNB4CHRNA3 | |
| SCHEMBL522561 | 0.79 | TSHR (0.44) | CHRNB2CHRNA4EPHX2CHRNB4CHRNA3 | |
| SCHEMBL7149632 | 0.79 | FOLH1 (0.35) | CHRNB2CHRNA4EPHX2CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL31735305 | 0.73 | TSHR (0.46) | CHRNB2CHRNA4EPHX2CHRNB4CHRNA3 | |
| SCHEMBL697966 | 0.72 | TSHR (0.50) | EPHX2TSHRMEN1KMT2A | |
| SCHEMBL27325446 | 0.70 | TSHR (0.43) | EPHX2TSHRMEN1KMT2A | |
| SCHEMBL6749042 | 0.70 | CCR5 (0.35) | CHRNB2CHRNA4CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL1037020 | 0.70 | KMT2A (0.52) | CHRNB2CHRNA4CHRNB4CHRNA3TSHR | |
| SCHEMBL31364853 | 0.70 | SMN1; SMN2 (0.47) | CHRNB2CHRNA4EPHX2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040092737-A1 | Benzopiperidine derivatives | EISAI CO., LTD. | 2004-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092737-A1 | Benzopiperidine derivatives | HLA-DRB1, HRH1, HRH2 | CHRNB2 3548/4885CHRNA4 2207/4885EPHX2 1799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.