Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 9/20 | 0.34 |
| ▸ | NPC1 | O15118 | 8/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.34 |
| ▸ | RELA | Q04206 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6745548 | 0.85 | HDAC6 (0.36) | HDAC6SMN1; SMN2NFKB1MEN1KMT2A | |
| SCHEMBL6749156 | 0.85 | ALDH1A1 (0.40) | HDAC6ALDH1A1POLBMAPTPKM | |
| SCHEMBL6749215 | 0.83 | HDAC6 (0.34) | HDAC6ALDH1A1 | |
| SCHEMBL6749216 | 0.83 | HDAC6 (0.34) | HDAC6ALDH1A1 | |
| SCHEMBL6749127 | 0.82 | MAPT (0.39) | HDAC6RAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL6749131 | 0.82 | MAPT (0.39) | HDAC6RAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL6745841 | 0.81 | GAA (0.34) | HDAC6SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL6747666 | 0.81 | KDM4E (0.40) | HDAC6SMN1; SMN2KMT2AALDH1A1GAA | |
| SCHEMBL6749394 | 0.81 | HDAC6 (0.34) | HDAC6 | |
| SCHEMBL6752015 | 0.81 | HDAC6 (0.37) | HDAC6SMN1; SMN2NFKB1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040092737-A1 | Benzopiperidine derivatives | EISAI CO., LTD. | 2004-05-13 | — | — | US | disclosed |
| US-6518423-B1 | These compounds are useful as drugs efficacious in the prevention and treatment of these various inflammatory diseases and immunologic diseases, such as rheumatoid arthritis, atopic dermatitis, psoriasis, asthma, and | EISAI CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-0934941-A1 | BENZOPIPERIDINE DERIVATIVES | Eisai Co., Ltd. (JP) | 1999-08-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092737-A1 | Benzopiperidine derivatives | HLA-DRB1, HRH1, HRH2 | HDAC6 1953/4885RAB9A 1768/4885NPC1 2875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.