Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | CA2 | P00918 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL673524 | 0.85 | CA2 (0.48) | TSHRCA2ALDH1A1CYP3A4TDP1 | |
| Acrylic Acid SCHEMBL1741910 | 0.82 | TSHR (0.56) | TSHRCA2ALDH1A1CYP3A4TDP1 | |
| Acrylic Acid SCHEMBL4448295 | 0.82 | TSHR (0.56) | TSHRCA2ALDH1A1CYP3A4TDP1 | |
| Acrylic Acid SCHEMBL3835470 | 0.82 | ALDH1A1 (0.67) | TSHRCA2ALDH1A1CYP3A4TDP1 | |
| SCHEMBL675317 | 0.81 | ALDH1A1 (0.54) | TSHRCA2ALDH1A1CYP3A4TDP1 | |
| Acrylic Acid SCHEMBL6133499 | 0.81 | ALDH1A1 (0.64) | TSHRCA2ALDH1A1CYP3A4TDP1 | |
| 2-Ethylhexanoic Acid SCHEMBL672844 | 0.79 | CA2 (0.69) | TSHRCA2ALDH1A1CYP3A4TDP1 | |
| Acrylic Acid SCHEMBL2306705 | 0.79 | TSHR (0.66) | TSHRCA2ALDH1A1CYP3A4TDP1 | |
| Hydrochloric Acid SCHEMBL15529297 | 0.79 | ALDH1A1 (0.52) | TSHRCA2ALDH1A1CYP3A4TDP1 | |
| Acrylic Acid SCHEMBL28806929 | 0.78 | TSHR (0.64) | TSHRCA2ALDH1A1CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10131722-B2 | Method for preparing terminal-modified conjugated diene polymer, terminal-modified conjugated diene polymer, rubber composition and tire | BRIDGESTONE CORPORATION (JP) | 2018-11-20 | — | — | US | disclosed |
| US-20170275400-A1 | METHOD FOR PREPARING TERMINAL-MODIFIED CONJUGATED DIENE POLYMER, TERMINAL-MODIFIED CONJUGATED DIENE POLYMER, RUBBER COMPOSITION AND TIRE | BRIDGESTONE CORPORATION (JP) | 2017-09-28 | — | — | US | disclosed |
| EP-3184554-A1 | METHOD FOR MANUFACTURING CONJUGATED DIENE POLYMER WITH MODIFIED END, CONJUGATED DIENE POLYMER WITH MODIFIED END, RUBBER COMPOSITION, AND TIRE | Bridgestone Corporation (JP) | 2017-06-28 | — | — | EP | disclosed |
| EP-1873168-B1 | MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES | BRIDGESTONE CORP (JP) | 2012-12-12 | — | — | EP | disclosed |
| US-7968652-B2 | Modified conjugated diene copolymer, rubber compositions and tires | BRIDGESTONE CORPORATION (JP) | 2011-06-28 | — | — | US | disclosed |
| US-20090292043-A1 | MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES | BRIDGESTONE CORPORATION (JP) | 2009-11-26 | — | — | US | disclosed |
| EP-1873168-A1 | MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES | Bridgestone Corporation (JP) | 2008-01-02 | — | — | EP | disclosed |