Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 19/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 17/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6744670 | 0.90 | PTGS2 (0.50) | PTGS2PTGS1 | |
| SCHEMBL6736233 | 0.85 | PTGS2 (0.60) | PTGS2PTGS1CA12CA1CA2 | |
| SCHEMBL6747465 | 0.84 | PTGS2 (0.45) | PTGS2PTGS1 | |
| SCHEMBL6725774 | 0.83 | PTGS2 (0.70) | PTGS2PTGS1 | |
| SCHEMBL6732850 | 0.78 | PTGS2 (0.69) | PTGS2PTGS1 | |
| SCHEMBL6729192 | 0.76 | PTGS2 (0.52) | PTGS2PTGS1 | |
| SCHEMBL6300780 | 0.76 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL6732162 | 0.76 | PTGS2 (0.49) | PTGS2PTGS1 | |
| SCHEMBL6739229 | 0.76 | PTGS2 (0.49) | PTGS2PTGS1 | |
| SCHEMBL6722672 | 0.74 | PTGS2 (0.60) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699884-B2 | ANTIINFLAMMATORY CYCLOOXYGENASE INHIBITORS. | PHARMACIA CORPORATION | 2004-03-02 | — | — | US | claimed |