SCHEMBL6747775

SCHEMBL6747775

COC(=O)C(=O)c1ccccc1O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.64
TSHR P16473 2/20 0.64
HPGD P15428 8/20 0.50
KDM4E B2RXH2 7/20 0.50
ALDH1A1 P00352 6/20 0.50
SMN1; SMN2 Q16637 4/20 0.50
GAA P10253 3/20 0.50
HIF1A Q16665 2/20 0.50
CA12 O43570 2/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA7 P43166 2/20 0.50
CA9 Q16790 2/20 0.50
CA14 Q9ULX7 2/20 0.50
MPO P05164 1/20 0.50
HMGB1 P09429 1/20 0.50
CA4 P22748 1/20 0.50
CA6 P23280 1/20 0.50
NAPRT Q6XQN6 1/20 0.50
HSD17B10 Q99714 5/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL27472958 0.98 LMNA (0.62) LMNATSHRHPGDKDM4EALDH1A1
SCHEMBL10698244 0.80 LMNA (0.60) LMNATSHRHPGDKDM4EALDH1A1
SCHEMBL27473286 0.80 LMNA (0.60) LMNATSHRHPGDKDM4EALDH1A1
Catechol SCHEMBL27785718 0.80 TSHR (0.58) LMNATSHRHPGDKDM4EALDH1A1
SCHEMBL29861559 0.79 KDM4E (0.67) LMNATSHRHPGDKDM4EALDH1A1
SCHEMBL9797513 0.79 KDM4E (0.67) LMNATSHRHPGDKDM4EALDH1A1
SCHEMBL2705722 0.79 NPC1 (0.49) LMNATSHRHPGDKDM4EALDH1A1
SCHEMBL16045657 0.79 TSHR (0.59) LMNATSHRKDM4EALDH1A1CA1
SCHEMBL28765805 0.79 LMNA (0.58) LMNATSHRHPGDKDM4EALDH1A1
SCHEMBL7027565 0.79 TSHR (0.55) LMNATSHRHPGDKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6831197-B2 Intermediates, in particular for preparing fungicides BAYER AKTIENGESELLSCHAFT (DE) 2004-12-14 US disclosed
EP-1185505-B1 METHOD OF PRODUCING METHOXYIMINO ACETIC AMIDE BAYER CROPSCIENCE AG (DE) 2004-11-03 EP disclosed
US-20040147782-A1 Methods for producing 2-(2-hydroxyphenyl)-2-(alkoxyimino)-N-methylacetamide derivatives HUBSCH WALTER (DE) 2004-07-29 US disclosed
US-6700017-B1 ALKYLATION, OXIDATION BAYER AKTIENGESELLSCHAFT (DE) 2004-03-02 US disclosed
US-6660872-B1 In high yields BAYER AKTIENGESELLSCHAFT (DE) 2003-12-09 US disclosed
CN-1399628-A Methods for producing 2-(2-hydroxyphenyl)-2-(alkoxyimino)-n-methylacetamide derivatives BAYER AG (DE) 2003-02-26 CN disclosed
US-6359172-B1 Method of preparing 2- and 4-hydroxymandelic acid GERARD KESSELS SOCIEDAD ANONIMA, S.A. (ES) 2002-03-19 US disclosed
EP-1185505-A1 METHOD OF PRODUCING METHOXYIMINO ACETIC AMIDE Bayer Aktiengesellschaft (DE) 2002-03-13 EP disclosed
EP-0987245-B1 A method of preparing 2- and 4-hydroxymandelic acid GERARD KESSELS S A (ES) 2002-03-13 EP disclosed
WO-2000071504-A1 METHOD OF PRODUCING METHOXYIMINO ACETIC AMIDE BAYER AKTIENGESELLSCHAFT (DE) 2000-11-30 WO disclosed
EP-0987245-A1 A method of preparing 2- and 4-hydroxymandelic acid Gerard Kessels S.A. (ES) 2000-03-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040147782-A1 Methods for producing 2-(2-hydroxyphenyl)-2-(alkoxyimino)-N-methylacetamide derivatives AADAC, HACL2, AZI2 LMNA 1724/4885TSHR 4354/4885HPGD 107/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.