SCHEMBL10698244

SCHEMBL10698244

C=C(OC)C(=O)c1ccccc1O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.60
TSHR P16473 2/20 0.60
NPC1 O15118 3/20 0.49
HPGD P15428 8/20 0.49
HIF1A Q16665 2/20 0.49
CYP2C19 P33261 2/20 0.49
ALOX15 P16050 2/20 0.49
CYP1A2 P05177 1/20 0.49
PGR P06401 1/20 0.49
CYP3A4 P08684 1/20 0.49
ADORA3 P0DMS8 1/20 0.49
AR P10275 1/20 0.49
CHRM1 P11229 1/20 0.49
TBXA2R P21731 1/20 0.49
SLC6A2 P23975 1/20 0.49
ADRA1A P35348 1/20 0.49
KDM4E B2RXH2 7/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
GAA P10253 2/20 0.47
MPO P05164 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Salicylic Acid SCHEMBL28188577 0.80 HPGD (0.62) LMNATSHRNPC1HPGDHIF1A
SCHEMBL6747775 0.80 LMNA (0.64) LMNATSHRNPC1HPGDHIF1A
SCHEMBL8672590 0.79 CES2 (0.61) TSHRHPGDCYP2C19CYP1A2ALDH1A1
Water SCHEMBL27472958 0.78 LMNA (0.62) LMNATSHRNPC1HPGDHIF1A
SCHEMBL31107414 0.78 KDM4E (0.52) LMNATSHRNPC1HPGDHIF1A
Methyl Salicylate SCHEMBL30721422 0.78 LMNA (0.96) LMNATSHRHPGDHIF1AALOX15
SCHEMBL5852958 0.78 KDM4E (0.52) LMNATSHRNPC1HPGDHIF1A
SCHEMBL27473286 0.77 LMNA (0.60) LMNATSHRNPC1HPGDHIF1A
SCHEMBL9797513 0.76 KDM4E (0.67) LMNATSHRNPC1HPGDHIF1A
SCHEMBL29861559 0.76 KDM4E (0.67) LMNATSHRNPC1HPGDHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0251082-A2 Substituted acrylic acid esters and fungicides containing these compounds BASF Aktiengesellschaft (DE) 1988-01-07 EP disclosed