SCHEMBL6747883

SCHEMBL6747883

O=S(=O)(O)c1cc2cccc(O)c2c(O)c1S(=O)(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
DNMT1 P26358 1/20 0.53
CACNA1B Q00975 1/20 0.53
APBA1 Q02410 1/20 0.53
MCL1 Q07820 1/20 0.53
APOBEC3G Q9HC16 1/20 0.53
MAPK1 P28482 3/20 0.45
CDK2 P24941 2/20 0.45
KDM4E B2RXH2 2/20 0.45
INPPL1 O15357 1/20 0.45
NSD2 O96028 1/20 0.45
TP53 P04637 1/20 0.45
POLB P06746 1/20 0.45
CYP3A4 P08684 1/20 0.45
GAA P10253 1/20 0.45
MAPT P10636 1/20 0.45
THRB P10828 1/20 0.45
PABPC1 P11940 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4730731 0.84 ALDH1A1 (0.43) ALDH1A1MEN1KMT2ADNMT1CACNA1B
SCHEMBL11047153 0.84 AURKA (0.45) ALDH1A1MEN1KMT2ADNMT1CACNA1B
SCHEMBL2161129 0.84 AURKA (0.49) ALDH1A1MEN1KMT2ADNMT1CACNA1B
SCHEMBL29495118 0.82 MEN1 (0.52) ALDH1A1MEN1KMT2ADNMT1CACNA1B
SCHEMBL4383279 0.81 AURKA (0.49) ALDH1A1MEN1KMT2ADNMT1CACNA1B
SCHEMBL27412761 0.77 AURKA (0.51) ALDH1A1MEN1KMT2ADNMT1CACNA1B
SCHEMBL28757570 0.77 AURKA (0.51) ALDH1A1MEN1KMT2ADNMT1CACNA1B
SCHEMBL358296 0.77 CYP2D6 (0.57) ALDH1A1MEN1KMT2AMAPK1MAPT
SCHEMBL5246088 0.75 AURKB (0.53) DNMT1MCL1MAPK1CDK2NSD2
SCHEMBL28020173 0.75 PTPN11 (0.41) ALDH1A1MEN1KMT2AMAPK1CDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6159270-A DEMETALLIZATION OF A SOIL ENVIRONMENT CONTAINING TOXIC METALS BY PLANTING AT LEAST ONE PLANT, E.G. FAMILY BRASSICACEAE, AND MANIPULATING ITS GROWTH SO THE ROOTS WILL ABSORB THE METALS; HARVESTING THE PLANTS; ADDING A CHELATING AGENT TO THE SOIL EDENSPACE SYSTEMS CORPORATION (US) 2000-12-12 US claimed
US-5785735-A DEMETALLIZATION OF SOILS, MANIPULATING THE GROWTH OF CROPS AND ABSORPTION OF METALS EDENSPACE SYSTEMS CORPORATION 1998-07-28 US claimed
EP-0701621-A1 PHYTOREMEDIATION OF METALS PHYTOTECH, INC. (US) 1996-03-20 EP claimed
WO-1994029466-A1 PHYTOREMEDIATION OF METALS PHYTOTECH, INC. (US) 1994-12-22 WO claimed
US-20040172670-A1 Maize yellow stripe1 and related genes NIH-DEITR 2004-09-02 US disclosed
EP-1352075-A2 MAIZE YELLOW STRIPE1 AND RELATED GENES YALE UNIVERSITY (US) 2003-10-15 EP disclosed
WO-2002040688-A9 MAIZE YELLOW STRIPE1 AND RELATED GENES UNIV YALE (US) 2003-02-13 WO disclosed
WO-2002040688-A2 MAIZE YELLOW STRIPE1 AND RELATED GENES YALE UNIVERSITY (US) 2002-05-23 WO disclosed
US-6159270-A DEMETALLIZATION OF A SOIL ENVIRONMENT CONTAINING TOXIC METALS BY PLANTING AT LEAST ONE PLANT, E.G. FAMILY BRASSICACEAE, AND MANIPULATING ITS GROWTH SO THE ROOTS WILL ABSORB THE METALS; HARVESTING THE PLANTS; ADDING A CHELATING AGENT TO THE SOIL EDENSPACE SYSTEMS CORPORATION (US) 2000-12-12 US disclosed
US-5928406-A REMEDIATING SOIL CONTAMINATED WITH CR(VI) BY REDUCING THE CR(VI) TO CR(III) IN THE SOIL; THE METHOD INVOLVES CONTACTING THE CONTAMINATED SOIL WITH A PLANT THAT ACCOMPLISHES THE REDUCTION RUTGERS, STATE UNIVERSITY OF NEW JERSEY, THE 1999-07-27 US disclosed
US-5917117-A Inducing hyperaccumulation of metals in plant shoots PHYTOTECH, INC. (US) 1999-06-29 US disclosed
US-5785735-A DEMETALLIZATION OF SOILS, MANIPULATING THE GROWTH OF CROPS AND ABSORPTION OF METALS EDENSPACE SYSTEMS CORPORATION 1998-07-28 US disclosed
EP-0701621-A1 PHYTOREMEDIATION OF METALS PHYTOTECH, INC. (US) 1996-03-20 EP disclosed
WO-1994029466-A1 PHYTOREMEDIATION OF METALS PHYTOTECH, INC. (US) 1994-12-22 WO disclosed
US-4033945-A Water-soluble trisazo 8-amino-naphthol-1 dyes CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) 1977-07-05 US disclosed