SCHEMBL6747894

SCHEMBL6747894

O=C(O)C1CCc2cc(OCc3ccccc3)ccc2C1

nearest known ligand 0.68

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FAAH O00519 15/20 0.68
FFAR1 O14842 1/20 0.61
HRH3 Q9Y5N1 3/20 0.55
CYP2D6 P10635 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6751368 0.89 FAAH (0.67) FAAHFFAR1HRH3
SCHEMBL8769199 0.88 FAAH (0.69) FAAHFFAR1HRH3
SCHEMBL630776 0.86 FAAH (0.64) FAAHFFAR1
SCHEMBL629707 0.85 FAAH (0.60) FAAHHRH3CYP2D6
SCHEMBL8536279 0.84 FAAH (0.62) FAAH
SCHEMBL10197642 0.83 FAAH (0.58) FAAHHRH3CYP2D6
SCHEMBL9022793 0.83 FAAH (0.63) FAAHHRH3
SCHEMBL18983590 0.83 HRH3 (0.59) FAAHHRH3CYP2D6
SCHEMBL17067903 0.81 FAAH (1.00) FAAH
SCHEMBL14378614 0.81 FFAR1 (0.60) FAAHFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0617109-B1 Liquid crystal material, liquid crystal composition and liquid crystal element MITSUI PETROCHEMICAL IND (JP) 1997-09-17 EP claimed
US-5422039-A Having a chiral center-containing a tetralinylene ring as well as a second chiral center; cells having high temperature operating range; high switching speed, low voltage and stable contrast MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-06-06 US claimed
EP-0617109-A1 Liquid crystal material, liquid crystal composition and liquid crystal element MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-09-28 EP claimed
US-6703082-B1 VARIOUS NAPHTHALENE-CONTAINING LIQUID CRYSTALS DISPLAYTECH, INC. 2004-03-09 US disclosed
JP-2000229915-A TETRALIN COMPOUND AND LIQUID CRYSTAL MATERIAL MITSUI CHEMICALS INC 2000-08-22 JP disclosed
US-5776365-A COMPOUNDS WITH OPTICAL ACTIVITY AND SWITCHES FOR CONTRAST MITSUI CHEMICALS, INC. (JP) 1998-07-07 US disclosed
US-5725798-A CARBOXYLIC ESTERS FOR ELECTRICAL APPARATUS, SWITCHES AND CONTRAST MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1998-03-10 US disclosed
EP-0549347-B1 Novel carboxylate compounds, liquid crystal materials, liquid crystal compositions and liquid crystal elements MITSUI PETROCHEMICAL IND (JP) 1997-10-29 EP disclosed
EP-0617109-B1 Liquid crystal material, liquid crystal composition and liquid crystal element MITSUI PETROCHEMICAL IND (JP) 1997-09-17 EP disclosed
EP-0566380-B1 Carboxylic acid ester compound, liquid crystal material, liquid crystal compositions and liquid crystal element MITSUI PETROCHEMICAL IND (JP) 1997-08-06 EP disclosed
EP-0566379-B1 Tetralin compound, liquid crystal material, liquid crystal composition and liquid crystal element MITSUI PETROCHEMICAL IND (JP) 1997-07-23 EP disclosed
US-5346646-A Tetralin compound, liquid crystal material, liquid crystal composition and liquid crystal element MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-09-13 US disclosed
US-5322639-A Display elements; high speed switching MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-06-21 US disclosed
EP-0566379-A2 Tetralin compound, liquid crystal material, liquid crystal composition and liquid crystal element MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-10-20 EP disclosed
EP-0566380-A2 Carboxylic acid ester compound, liquid crystal material, liquid crystal compositions and liquid crystal element MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-10-20 EP disclosed
EP-0549347-A1 Novel carboxylate compounds, liquid crystal materials, liquid crystal compositions and liquid crystal elements MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-06-30 EP disclosed
EP-0465048-A2 Carboxylic acid ester compound, liquid crystal compound, liquid crystal composition, liquid crystal element and light modulation method MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-01-08 EP disclosed
US-4530919-A A 1,2,3,4-tetrahydronaphthalene carboxylic acid PFIZER INC. (US) 1985-07-23 US disclosed
US-4374148-A HYPOGLYCEMIC AGENTS PFIZER INC. (US) 1983-02-15 US disclosed
US-4305955-A ORAL HYPOGLYCEMIC AGENTS, CHROMAN-4-CARBOXYLIC ACID OR THIOCHROMAN-4-CARBOXYLIC ACID PFIZER INC. (US) 1981-12-15 US disclosed