Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 17/20 | 0.69 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9022793 | 0.95 | FAAH (0.63) | FAAHHRH3 | |
| SCHEMBL12472053 | 0.90 | FAAH (0.59) | FAAHHRH3 | |
| SCHEMBL6751368 | 0.89 | FAAH (0.67) | FAAHFFAR1HRH3 | |
| SCHEMBL346315 | 0.89 | FAAH (0.58) | FAAH | |
| SCHEMBL630776 | 0.89 | FAAH (0.64) | FAAHFFAR1 | |
| SCHEMBL6747894 | 0.88 | FAAH (0.68) | FAAHFFAR1HRH3 | |
| SCHEMBL345723 | 0.85 | FAAH (0.53) | FAAHFFAR1 | |
| SCHEMBL8536279 | 0.84 | FAAH (0.62) | FAAH | |
| SCHEMBL346357 | 0.84 | FAAH (0.54) | FAAH | |
| SCHEMBL629707 | 0.83 | FAAH (0.60) | FAAHHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7224005-A | — | — | None | — | — | JP | disclosed |
| US-9504675-B2 | Alpha-ketoheterocycles and methods of making and using | THE SCRIPPS RESEARCH INSTITUTE (US) | 2016-11-29 | — | — | US | disclosed |
| US-9504675-B2 | Alpha-ketoheterocycles and methods of making and using | THE SCRIPPS RESEARCH INSTITUTE (US) | 2016-11-29 | — | — | US | disclosed |
| US-9504675-B2 | Alpha-ketoheterocycles and methods of making and using | THE SCRIPPS RESEARCH INSTITUTE (US) | 2016-11-29 | — | — | US | disclosed |
| EP-2670245-B1 | ALPHA-KETOHETEROCYCLES AND METHODS OF MAKING AND USING | SCRIPPS RESEARCH INST (US) | 2015-09-09 | — | — | EP | disclosed |
| EP-2670245-B1 | ALPHA-KETOHETEROCYCLES AND METHODS OF MAKING AND USING | SCRIPPS RESEARCH INST (US) | 2015-09-09 | — | — | EP | disclosed |
| US-20130338196-A1 | ALPHA-KETOHETEROCYCLES AND METHODS OF MAKING AND USING | THE SCRIPPS RESEARCH INSTITUTE (US) | 2013-12-19 | — | — | US | disclosed |
| EP-0617109-B1 | Liquid crystal material, liquid crystal composition and liquid crystal element | MITSUI PETROCHEMICAL IND (JP) | 1997-09-17 | — | — | EP | disclosed |
| JP-H07224005-A | CARBOXYLIC ESTES AND LIQUID CRYSTAL ADDITIVES | MITSUI PETROCHEM IND LTD | 1995-08-22 | — | — | JP | disclosed |
| US-5422039-A | Having a chiral center-containing a tetralinylene ring as well as a second chiral center; cells having high temperature operating range; high switching speed, low voltage and stable contrast | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1995-06-06 | — | — | US | disclosed |
| EP-0617109-A1 | Liquid crystal material, liquid crystal composition and liquid crystal element | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1994-09-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130338196-A1 | ALPHA-KETOHETEROCYCLES AND METHODS OF MAKING AND USING | FAAH, FAAH2, CNR2 | FAAH 1/4885FFAR1 89/4885HRH3 100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.