Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | NOS2 | P35228 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 4/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | PNMT | P11086 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6185724 | 0.84 | CYP2D6 (0.35) | ALDH1A1SMN1; SMN2CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL6186368 | 0.84 | CYP2D6 (0.44) | ALDH1A1SMN1; SMN2CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL6189779 | 0.76 | CYP3A4 (0.36) | CYP2D6SLC6A2SLC6A4NOS2ALOX5AP | |
| Hydrochloric Acid SCHEMBL6748191 | 0.75 | CYP3A4 (0.36) | CYP2D6SLC6A2SLC6A4NOS2ALOX5AP | |
| SCHEMBL6750954 | 0.74 | CYP2D6 (0.42) | ALDH1A1CYP2D6SLC6A2SLC6A4NOS2 | |
| SCHEMBL6188753 | 0.74 | CYP2D6 (0.42) | ALDH1A1SMN1; SMN2MEN1KMT2ACYP2D6 | |
| SCHEMBL6748041 | 0.72 | CYP2D6 (0.39) | ALDH1A1CYP2D6SLC6A2SLC6A4NOS2 | |
| SCHEMBL6185529 | 0.71 | CYP2D6 (0.40) | ALDH1A1KMT2ACYP2D6SLC6A2SLC6A4 | |
| SCHEMBL6746295 | 0.71 | CYP2D6 (0.40) | ALDH1A1KMT2ACYP2D6SLC6A2SLC6A4 | |
| SCHEMBL231181 | 0.71 | CYP2D6 (0.40) | ALDH1A1KMT2ACYP2D6SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040242871-A1 | Novel arylheteroalkylamine derivatives | ASTRAZENECA AB (SE) | 2004-12-02 | — | — | US | claimed |
| US-20040242871-A1 | Novel arylheteroalkylamine derivatives | ASTRAZENECA AB (SE) | 2004-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242871-A1 | Novel arylheteroalkylamine derivatives | CYP1A1, NOS3, NOS1 | ALDH1A1 495/4885SMN1; SMN2 3507/4885MEN1 4748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.