SCHEMBL6748182

SCHEMBL6748182

Nc1cc(O)c(NC(=O)c2ccc(Cl)c(Cl)c2)cc1Cl

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.54
KMT2A Q03164 3/20 0.54
KDM4E B2RXH2 2/20 0.54
MAPT P10636 2/20 0.54
NPC1 O15118 1/20 0.54
PKM P14618 1/20 0.54
RAB9A P51151 1/20 0.54
BCAT2 O15382 1/20 0.52
MAOB P27338 2/20 0.47
MAOA P21397 1/20 0.47
ACHE P22303 1/20 0.46
KCNQ3 O43525 1/20 0.46
KCNQ2 O43526 1/20 0.46
KCNE1 P15382 1/20 0.46
KCNQ1 P51787 1/20 0.46
KCNMA1 Q12791 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7528116 0.85 KCNMA1 (0.50) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL9492060 0.84 KCNMA1 (0.61) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL7294749 0.82 RAB9A (0.62) MEN1KMT2AKDM4EMAPTNPC1
SCHEMBL11787853 0.80 MEN1 (0.53) MEN1KMT2AKDM4EMAPTNPC1
SCHEMBL6748184 0.78 CXCR2 (0.58) MEN1KMT2AKDM4EMAPTNPC1
SCHEMBL10603095 0.78 CA1 (0.58) MEN1KMT2AMAPTSMN1; SMN2NPSR1
SCHEMBL9814400 0.78 CYP1A2 (0.61) KMT2AKDM4EMAPTNPC1RAB9A
SCHEMBL4670177 0.76 CYP1A2 (0.42) KDM4ENPC1RAB9AKCNMA1HDAC1
Hydrochloric Acid SCHEMBL6408103 0.76 GAA (0.39) KDM4ENPC1RAB9AKCNMA1POLB
SCHEMBL4669177 0.76 GAA (0.39) KCNMA1HDAC1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103130676-A Preparation method of 2-(3,4-dichloro-benzamido)-4-chlorine-5-aminophenol SHENYANG RES INST OF THE PHOTOGRAPHIC MATERIALS & CHEMICAL INDUSTRY 2013-06-05 CN claimed
CN-103130676-B Preparation method of 2-(3,4-dichloro-benzamido)-4-chlorine-5-aminophenol SHENYANG RES INST OF PHOTOGRAPHIC MATERIALS & CHEMICAL INDUSTRY 2015-03-11 CN disclosed
CN-103130676-B Preparation method of 2-(3,4-dichloro-benzamido)-4-chlorine-5-aminophenol SHENYANG RES INST OF PHOTOGRAPHIC MATERIALS & CHEMICAL INDUSTRY 2015-03-11 CN disclosed
CN-103130676-B Preparation method of 2-(3,4-dichloro-benzamido)-4-chlorine-5-aminophenol SHENYANG RES INST OF PHOTOGRAPHIC MATERIALS & CHEMICAL INDUSTRY 2015-03-11 CN disclosed
CN-103130676-A Preparation method of 2-(3,4-dichloro-benzamido)-4-chlorine-5-aminophenol SHENYANG RES INST OF THE PHOTOGRAPHIC MATERIALS & CHEMICAL INDUSTRY 2013-06-05 CN disclosed
CN-103130676-A Preparation method of 2-(3,4-dichloro-benzamido)-4-chlorine-5-aminophenol SHENYANG RES INST OF THE PHOTOGRAPHIC MATERIALS & CHEMICAL INDUSTRY 2013-06-05 CN disclosed
CN-103130676-A Preparation method of 2-(3,4-dichloro-benzamido)-4-chlorine-5-aminophenol SHENYANG RES INST OF THE PHOTOGRAPHIC MATERIALS & CHEMICAL INDUSTRY 2013-06-05 CN disclosed
US-6699650-B1 YIELD CYAN IMAGES OF GOOD HUE, WITH GOOD STABILITY TO HEAT, HUMIDITY AND LIGHT, WHILST RETAINING THE OTHER PROPERTIES DESIRABLE FOR GOOD PHOTOGRAPHIC PERFORMANCE EASTMAN KODAK COMPANY 2004-03-02 US disclosed
EP-1145078-B1 PHOTOGRAPHIC COUPLERS HAVING IMPROVED IMAGE DYE LIGHT STABILITY EASTMAN KODAK CO (US) 2003-09-10 EP disclosed
EP-1145078-A1 PHOTOGRAPHIC COUPLERS HAVING IMPROVED IMAGE DYE LIGHT STABILITY EASTMAN KODAK COMPANY (US) 2001-10-17 EP disclosed
CN-1309328-A Photographic material, dispersion, compound and method EASTMAN KODAK CO (US) 2001-08-22 CN disclosed
EP-1113330-A1 Photographic element and process EASTMAN KODAK COMPANY (US) 2001-07-04 EP disclosed
US-6190851-B1 CYAN DYE FORMING COUPLER EASTMAN KODAK COMPANY 2001-02-20 US disclosed
WO-2000038013-A1 PHOTOGRAPHIC COUPLERS HAVING IMPROVED IMAGE DYE LIGHT STABILITY EASTMAN KODAK COMPANY (US) 2000-06-29 WO disclosed
US-6004738-A Photographic elements containing cyan dye-forming coupler, coupler solvent and bisphenol derivative EASTMAN KODAK COMPANY (US) 1999-12-21 US disclosed
EP-0913729-A1 Photographic elements containing cyan dye-forming coupler, coupler solvent and bisphenol derivative EASTMAN KODAK COMPANY (US) 1999-05-06 EP disclosed