Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.30 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9485033 | 0.78 | CYP1A2 (0.44) | CA12CA1CA9ALDH1A1ALDH2 | |
| Hydrochloric Acid SCHEMBL22771570 | 0.76 | CYP1A2 (0.43) | CA12CA1CA9ALDH1A1ALDH2 | |
| SCHEMBL22353427 | 0.74 | CYP1A2 (0.46) | CA12CA1CA9ALDH1A1ALDH2 | |
| SCHEMBL609665 | 0.73 | CA12 (0.34) | CA12CA1CA9ALDH1A1ALDH2 | |
| SCHEMBL6050078 | 0.72 | CA12 (0.41) | CA12CA1CA9ALDH1A1ALDH2 | |
| SCHEMBL28591805 | 0.71 | CYP1A2 (0.43) | CA12CA1CA9ALDH1A1ALDH2 | |
| SCHEMBL1880050 | 0.71 | CA12 (0.44) | CA12CA1CA9ALDH1A1ALDH2 | |
| SCHEMBL976730 | 0.71 | — | — | |
| SCHEMBL28563186 | 0.70 | CA12 (0.39) | CA12CA1CA9ALDH1A1ALDH2 | |
| Hydrogen Peroxide SCHEMBL137835 | 0.70 | KDM5A (0.48) | CA12CA1CA9ALDH1A1ALDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1233669-B1 | BLOCKING AN ETHYLENE RESPONSE IN PLANTS USING CYCLOPROPENE DERIVATIVES | UNIV NORTH CAROLINA STATE (US) | 2004-02-25 | — | — | EP | disclosed |