Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | WRN | Q14191 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | DGKA | P23743 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | YWHAG | P61981 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28992200 | 0.82 | NAAA (0.43) | NAAAGAAALDH1A1HIF1AHTT | |
| SCHEMBL50301 | 0.78 | NAAA (0.64) | NAAAGAAALDH1A1HIF1AHTT | |
| SCHEMBL21333234 | 0.76 | NAAA (0.34) | NAAAGAAALDH1A1HIF1AHTT | |
| SCHEMBL17865592 | 0.75 | NAAA (0.47) | NAAAGAAALDH1A1HIF1AHTT | |
| Water SCHEMBL28123302 | 0.75 | NAAA (0.61) | NAAAGAAALDH1A1HIF1AHTT | |
| Ethylene SCHEMBL9937082 | 0.73 | NAAA (0.58) | NAAAGAAALDH1A1HIF1AHTT | |
| Ethylene SCHEMBL6759867 | 0.73 | NAAA (0.58) | NAAAGAAALDH1A1HIF1AHTT | |
| SCHEMBL28992178 | 0.72 | NAAA (0.49) | NAAAGAAALDH1A1HIF1AHTT | |
| SCHEMBL10030185 | 0.71 | HTT (0.64) | NAAAGAAHTTCYP1A2CYP2C19 | |
| SCHEMBL181724 | 0.71 | NAAA (0.56) | NAAAGAAALDH1A1HIF1AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101828552-A | Method with the cyclopropene derivatives blocking ethylene response in plants | UNIV NORTH CAROLINA STATE | 2010-09-15 | — | — | CN | claimed |
| EP-1233669-B1 | BLOCKING AN ETHYLENE RESPONSE IN PLANTS USING CYCLOPROPENE DERIVATIVES | UNIV NORTH CAROLINA STATE (US) | 2004-02-25 | — | — | EP | claimed |
| CN-1450859-A | method for blocking ethylene response in plants using cyclopropene derivatives | UNIV NORTH CAROLINA STATE (US) | 2003-10-22 | — | — | CN | claimed |
| EP-1233669-A2 | BLOCKING AN ETHYLENE RESPONSE IN PLANTS USING CYCLOPROPENE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2002-08-28 | — | — | EP | claimed |
| US-6365549-B2 | PRESERVATION | NORTH CAROLINA STATE UNIVERSITY | 2002-04-02 | — | — | US | claimed |
| US-20010019995-A1 | Methods of blocking an ethylene response in plants using cyclopropene derivatives | NORTH CAROLINA STATE UNIVERSITY | 2001-09-06 | — | — | US | claimed |
| WO-2001037663-A2 | BLOCKING AN ETHYLENE RESPONSE IN PLANTS USING CYCLOPROPENE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2001-05-31 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010019995-A1 | Methods of blocking an ethylene response in plants using cyclopropene derivatives | PRUNE1, NOTUM, FAR1 | NAAA 841/4885GAA 3622/4885ALDH1A1 3933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.