SCHEMBL6748356

SCHEMBL6748356

CC(=O)OCCCCCCCC1=CC1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.45
LMNA P02545 2/20 0.42
APOBEC3A P31941 1/20 0.42
APOBEC3G Q9HC16 1/20 0.42
PTGS2 P35354 1/20 0.40
TSHR P16473 3/20 0.39
TNKS2 Q9H2K2 1/20 0.39
CHRM5 P08912 3/20 0.37
CHRM1 P11229 3/20 0.37
CHRM3 P20309 3/20 0.37
CHRM2 P08172 2/20 0.37
CHRM4 P08173 2/20 0.37
RAD52 P43351 1/20 0.36
PGR P06401 1/20 0.35
HTR1A P08908 1/20 0.35
CHRNB2 P17787 1/20 0.35
TBXA2R P21731 1/20 0.35
CHRNB4 P30926 1/20 0.35
CHRNA3 P32297 1/20 0.35
CHRNA7 P36544 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL250642 0.77 ALDH1A1 (0.70) ALDH1A1LMNAAPOBEC3AAPOBEC3GPTGS2
SCHEMBL273326 0.77 ALDH1A1 (0.70) ALDH1A1LMNAAPOBEC3AAPOBEC3GPTGS2
SCHEMBL29414114 0.77 ALDH1A1 (0.70) ALDH1A1LMNAAPOBEC3AAPOBEC3GPTGS2
SCHEMBL4441760 0.77 ALDH1A1 (0.70) ALDH1A1LMNAAPOBEC3AAPOBEC3GPTGS2
SCHEMBL8607908 0.77 ALDH1A1 (0.70) ALDH1A1LMNAAPOBEC3AAPOBEC3GPTGS2
SCHEMBL11491818 0.77 ALDH1A1 (0.70) ALDH1A1LMNAAPOBEC3AAPOBEC3GPTGS2
SCHEMBL15299079 0.77 ALDH1A1 (0.70) ALDH1A1LMNAAPOBEC3AAPOBEC3GPTGS2
SCHEMBL5136503 0.77 ALDH1A1 (0.70) ALDH1A1LMNAAPOBEC3AAPOBEC3GPTGS2
SCHEMBL11492305 0.77 ALDH1A1 (0.70) ALDH1A1LMNAAPOBEC3AAPOBEC3GPTGS2
SCHEMBL28084292 0.77 ALDH1A1 (0.70) ALDH1A1LMNAAPOBEC3AAPOBEC3GPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1233669-B1 BLOCKING AN ETHYLENE RESPONSE IN PLANTS USING CYCLOPROPENE DERIVATIVES UNIV NORTH CAROLINA STATE (US) 2004-02-25 EP claimed
EP-1233669-A2 BLOCKING AN ETHYLENE RESPONSE IN PLANTS USING CYCLOPROPENE DERIVATIVES NORTH CAROLINA STATE UNIVERSITY (US) 2002-08-28 EP claimed
US-6365549-B2 PRESERVATION NORTH CAROLINA STATE UNIVERSITY 2002-04-02 US claimed
US-20010019995-A1 Methods of blocking an ethylene response in plants using cyclopropene derivatives NORTH CAROLINA STATE UNIVERSITY 2001-09-06 US claimed
WO-2001037663-A2 BLOCKING AN ETHYLENE RESPONSE IN PLANTS USING CYCLOPROPENE DERIVATIVES NORTH CAROLINA STATE UNIVERSITY (US) 2001-05-31 WO claimed
EP-1233669-B1 BLOCKING AN ETHYLENE RESPONSE IN PLANTS USING CYCLOPROPENE DERIVATIVES UNIV NORTH CAROLINA STATE (US) 2004-02-25 EP disclosed
EP-1233669-A2 BLOCKING AN ETHYLENE RESPONSE IN PLANTS USING CYCLOPROPENE DERIVATIVES NORTH CAROLINA STATE UNIVERSITY (US) 2002-08-28 EP disclosed
US-6365549-B2 PRESERVATION NORTH CAROLINA STATE UNIVERSITY 2002-04-02 US disclosed
US-20010019995-A1 Methods of blocking an ethylene response in plants using cyclopropene derivatives NORTH CAROLINA STATE UNIVERSITY 2001-09-06 US disclosed
WO-2001037663-A2 BLOCKING AN ETHYLENE RESPONSE IN PLANTS USING CYCLOPROPENE DERIVATIVES NORTH CAROLINA STATE UNIVERSITY (US) 2001-05-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010019995-A1 Methods of blocking an ethylene response in plants using cyclopropene derivatives PRUNE1, NOTUM, FAR1 ALDH1A1 3933/4885LMNA 3181/4885APOBEC3A 593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.