Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT2 | O60551 | 4/20 | 0.40 |
| ▸ | NMT1 | P30419 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3909702 | 0.75 | PPARG (0.49) | MAPK1TDP1SLC40A1PPARGDRD4 | |
| SCHEMBL377363 | 0.71 | PPARG (0.66) | PPARG | |
| SCHEMBL377531 | 0.71 | PPARG (0.66) | PPARG | |
| Trifluoroacetic Acid SCHEMBL7711566 | 0.70 | PPARG (0.50) | PPARG | |
| SCHEMBL31430627 | 0.67 | NPC1 (0.56) | ALDH1A1GAAHTTSLC40A1DRD2 | |
| SCHEMBL3798973 | 0.66 | NPC1 (0.45) | ALDH1A1MAPK1GAATDP1HTT | |
| SCHEMBL5274283 | 0.66 | NPC1 (0.44) | KDM4EALDH1A1DRD2DRD4DRD3 | |
| Trifluoroacetic Acid SCHEMBL7705739 | 0.66 | PPARG (0.43) | PPARG | |
| SCHEMBL2786491 | 0.66 | PPARG (0.53) | PPARGDRD4 | |
| SCHEMBL7922696 | 0.66 | PPARG (0.64) | ALDH1A1PPARGDRD4RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040171692-A1 | Modulation of bone formation | ANDREW SCUTT (GB) | 2004-09-02 | — | — | US | claimed |
| JP-2003522787-A | — | — | 2003-07-29 | — | — | JP | claimed |
| US-20030139372-A1 | Modulation of bone formation | UNIVERSITY OF SHEFFIELD (GB) | 2003-07-24 | — | — | US | claimed |
| EP-1259233-A1 | MODULATION OF BONE FORMATION | THE UNIVERSITY OF SHEFFIELD (GB) | 2002-11-27 | — | — | EP | claimed |
| WO-2001060355-A1 | MODULATION OF BONE FORMATION | UNIVERSITY OF SHEFFIELD (GB) | 2001-08-23 | — | — | WO | claimed |
| US-20040171692-A1 | Modulation of bone formation | ANDREW SCUTT (GB) | 2004-09-02 | — | — | US | disclosed |
| US-20030139372-A1 | Modulation of bone formation | UNIVERSITY OF SHEFFIELD (GB) | 2003-07-24 | — | — | US | disclosed |
| EP-1259233-A1 | MODULATION OF BONE FORMATION | THE UNIVERSITY OF SHEFFIELD (GB) | 2002-11-27 | — | — | EP | disclosed |
| WO-2001060355-A1 | MODULATION OF BONE FORMATION | UNIVERSITY OF SHEFFIELD (GB) | 2001-08-23 | — | — | WO | disclosed |