Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | TOP1 | P11387 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | ARG2 | P78540 | 1/20 | 0.48 |
| ▸ | NOS1 | P29475 | 3/20 | 0.42 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | GPR52 | Q9Y2T5 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 3/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL517737 | 1.00 | MAOB (0.56) | MAOBTOP1CA1CA2ARG2 | |
| SCHEMBL11097573 | 0.89 | MAOB (0.39) | MAOBTOP1CA1CA2ARG2 | |
| SCHEMBL9073479 | 0.86 | NOS1 (0.44) | MAOBTOP1CA1CA2ARG2 | |
| SCHEMBL9298956 | 0.83 | MAOB (0.61) | MAOBTOP1CA1CA2ARG2 | |
| SCHEMBL2280548 | 0.83 | MAOB (0.61) | MAOBTOP1CA1CA2ARG2 | |
| SCHEMBL1233515 | 0.83 | MAOB (0.61) | MAOBTOP1CA1CA2ARG2 | |
| SCHEMBL2555173 | 0.83 | MAOB (0.61) | MAOBTOP1CA1CA2ARG2 | |
| SCHEMBL9111579 | 0.81 | MAOB (0.58) | MAOBTOP1CA1CA2ARG2 | |
| SCHEMBL6966016 | 0.81 | MAOB (0.58) | MAOBTOP1CA1CA2ARG2 | |
| SCHEMBL11974561 | 0.81 | MAOB (0.58) | MAOBTOP1CA1CA2ARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1092729-B1 | POLYMERIZATION CATALYST, NOVEL TRANSITION METAL COMPOUND, AND POLYMERIZATION METHOD AND COPOLYMER USING THEM | MITSUI CHEMICALS INC (JP) | 2012-09-26 | — | — | EP | disclosed |
| EP-1284734-B1 | ISOQUINOLINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | CUREGENICS LTD (IL) | 2008-05-21 | — | — | EP | disclosed |
| US-6703459-B1 | ORGANIC TRANSITION METAL COMPLEXES HAVING SPECIFIC STRUCTURE, WHICH CAN FORM COPOLYMERS HAVING LINKAGE FORMED BY MIGRATION OF ACTIVE HYDROGEN OF UNSATURATED MONOMER | MITSUI CHEMICALS, INC. (JP) | 2004-03-09 | — | — | US | disclosed |
| EP-1092729-A1 | POLYMERIZATION CATALYST, NOVEL TRANSITION METAL COMPOUND, AND POLYMERIZATION METHOD AND COPOLYMER USING THEM | Mitsui Chemicals, Inc. (JP) | 2001-04-18 | — | — | EP | disclosed |