Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | TOP1 | P11387 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ARG2 | P78540 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | C1S | P09871 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL517737 | 0.89 | MAOB (0.56) | MAOBCA2TOP1NOS1CYP3A4 | |
| SCHEMBL6748586 | 0.89 | MAOB (0.56) | MAOBCA2TOP1NOS1CYP3A4 | |
| SCHEMBL9073479 | 0.83 | NOS1 (0.44) | MAOBCA2TOP1NOS1CYP2D6 | |
| SCHEMBL11366685 | 0.78 | MAOB (0.46) | MAOBCA2TOP1CYP2D6CA1 | |
| SCHEMBL59859 | 0.77 | PTGER4 (0.42) | CYP3A4BLMALDH1A1MAPTHTT | |
| SCHEMBL29466952 | 0.77 | PTGER4 (0.42) | CYP3A4BLMALDH1A1MAPTHTT | |
| SCHEMBL3864569 | 0.75 | ALDH1A1 (0.42) | CYP3A4CYP2D6HIF1AMEN1KMT2A | |
| SCHEMBL8917566 | 0.74 | ALDH1A1 (0.50) | CA2HIF1AMEN1KMT2ACA1 | |
| SCHEMBL8917564 | 0.74 | ALDH1A1 (0.50) | CA2HIF1AMEN1KMT2ACA1 | |
| SCHEMBL27864784 | 0.74 | GABRR1 (0.46) | MAOBCYP2D6BLMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4446222-A | Method of preparing printing surface formed of polymeric resin containing polyamide and dicarboxylic acid diester | MATRIX UNLIMITED, INC. (US) | 1984-05-01 | — | — | US | disclosed |
| US-4345022-A | Process of recovering unpolymerized photopolymer from printing plates | MATRIX UNLIMITED, INC. (US) | 1982-08-17 | — | — | US | disclosed |
| US-4269930-A | ALONG WITH A PHOTOSENSITIZER AND POLYMERIZATION INHIBITOR; HARD, TOUGH GRAVURE PRINTING PLATES | MATRIX UNLIMITED, INC. (US) | 1981-05-26 | — | — | US | disclosed |