Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 9/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 5/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | PNP | P00491 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9068090 | 0.90 | HPRT1 (0.58) | HPRT1NOS1NOS3NOS2PNP | |
| SCHEMBL8149575 | 0.86 | HPRT1 (0.60) | HPRT1NOS1NOS3NOS2PNP | |
| SCHEMBL572051 | 0.85 | HPRT1 (0.59) | HPRT1NOS1PNP | |
| SCHEMBL8986621 | 0.85 | HPRT1 (0.56) | HPRT1NOS1NOS3NOS2PNP | |
| SCHEMBL3743947 | 0.84 | HPRT1 (0.56) | HPRT1NOS1NOS3NOS2KMT2A | |
| SCHEMBL146427 | 0.84 | HPRT1 (0.61) | HPRT1PNP | |
| SCHEMBL8446393 | 0.84 | HPRT1 (0.58) | HPRT1NOS1PNPMEN1KMT2A | |
| SCHEMBL22799106 | 0.83 | HPRT1 (0.57) | HPRT1MAPK1NOS1PNP | |
| SCHEMBL11378784 | 0.83 | HPRT1 (0.54) | HPRT1MAPK1NOS1NOS3NOS2 | |
| SCHEMBL8445573 | 0.82 | HPRT1 (0.53) | HPRT1MAPK1NOS1PNPMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040109896-A1 | Aqueous suspension eyedrops and process for producing the same | NOF CORPORATION (JP) | 2004-06-10 | — | — | US | claimed |
| EP-1366767-A1 | AQUEOUS SUSPENSION EYEDROPS AND PROCESS FOR PRODUCING THE SAME | NOF CORPORATION (JP) | 2003-12-03 | — | — | EP | claimed |
| EP-0741740-B1 | METHOD OF PREPARING UNSYMMETRICAL PHOSPHORIC ACID DIESTERS AND SALTS | ROCHE DIAGNOSTICS GMBH (DE) | 1999-04-07 | — | — | EP | claimed |
| US-5734042-A | Process for the production of asymmetrical phosphoric acid diesters | BOEHRINGER MANNHEIM GMBH (DE) | 1998-03-31 | — | — | US | claimed |
| US-4199574-A | Methods and compositions for treating viral infections and guanine acyclic nucleosides | BURROUGHS WELLCOME CO. (US) | 1980-04-22 | — | — | US | claimed |
| US-5734042-A | Process for the production of asymmetrical phosphoric acid diesters | BOEHRINGER MANNHEIM GMBH (DE) | 1998-03-31 | — | — | US | disclosed |
| US-5612348-A | Method of treating warts | RIVERS, JASON, M.D. (CA) | 1997-03-18 | — | — | US | disclosed |
| EP-0274025-A2 | Novel antiviral agents | SRI INTERNATIONAL (US) | 1988-07-13 | — | — | EP | disclosed |
| EP-0273169-A2 | Novel antiviral agents | SRI INTERNATIONAL (US) | 1988-07-06 | — | — | EP | disclosed |
| EP-0272446-A1 | Novel antiviral agents | SRI INTERNATIONAL (US) | 1988-06-29 | — | — | EP | disclosed |
| WO-1984004748-A2 | NOVEL ANTIVIRAL AGENTS | — | 1984-12-06 | — | — | WO | disclosed |