SCHEMBL3743947

SCHEMBL3743947

CCN1CNc2c1nc(N)[nH]c2=O

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 7/20 0.56
NOS1 P29475 6/20 0.41
NOS3 P29474 1/20 0.38
NOS2 P35228 1/20 0.38
USP2 O75604 1/20 0.35
CASP7 P55210 1/20 0.35
HSD17B10 Q99714 1/20 0.35
PAH P00439 1/20 0.35
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
GLA P06280 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
BLM P54132 1/20 0.34
PMP22 Q01453 1/20 0.34
KMT2A Q03164 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9364441 0.88 HPRT1 (0.60) HPRT1NOS1NOS3NOS2USP2
SCHEMBL21637016 0.86 HPRT1 (0.57) HPRT1NOS1NOS3NOS2
SCHEMBL9739844 0.84 HPRT1 (0.60) HPRT1NOS1NOS3NOS2USP2
SCHEMBL6748740 0.84 HPRT1 (0.57) HPRT1NOS1NOS3NOS2KMT2A
SCHEMBL489058 0.83 HPRT1 (0.56) HPRT1NOS1NOS3NOS2USP2
SCHEMBL9068090 0.82 HPRT1 (0.58) HPRT1NOS1NOS3NOS2USP2
SCHEMBL23892758 0.82 HPRT1 (0.54) HPRT1NOS1NOS3NOS2MAPT
SCHEMBL9278710 0.82 HPRT1 (0.54) HPRT1NOS1NOS3NOS2KMT2A
SCHEMBL11378784 0.81 HPRT1 (0.54) HPRT1NOS1NOS3NOS2ALDH1A1
SCHEMBL8447171 0.81 HPRT1 (0.57) HPRT1NOS1NOS3NOS2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109799313-B Nitrogen-doped carbon material nano enzyme based on nucleic acid base or derivative thereof, and preparation method and application thereof 南京大学 2021-07-27 CN claimed
CN-109799313-A Nitrogen-doped carbon material nano enzyme based on nucleic acid base or derivatives thereof and its preparation method and application 南京大学 2019-05-24 CN claimed
US-20240376538-A1 PRETREATMENT METHOD FOR DNA ADDUCTOMICS SAMPLES NATIONAL INSTITUTES OF HEALTH 2024-11-14 US disclosed
US-12054768-B2 Methods for detecting agglutination and compositions for use in practicing the same THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-08-06 US disclosed
EP-4123031-A1 METHODS FOR DETECTING AGGLUTINATION AND COMPOSITIONS FOR USE IN PRACTICING THE SAME The Regents of The University of California (US) 2023-01-25 EP disclosed
EP-3283638-B1 METHODS FOR DETECTING AGGLUTINATION AND USE OF KITS IN PRACTICING THE SAME UNIV CALIFORNIA (US) 2022-06-08 EP disclosed
US-20210403978-A1 METHODS FOR DETECTING AGGLUTINATION AND COMPOSITIONS FOR USE IN PRACTICING THE SAME THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2021-12-30 US disclosed
US-11149296-B2 Methods for detecting agglutination and compositions for use in practicing the same THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-10-19 US disclosed
CN-213924585-U Post-treatment system of halogenated pyrimidine 河北诚信集团有限公司 2021-08-10 CN disclosed
CN-109799313-B Nitrogen-doped carbon material nano enzyme based on nucleic acid base or derivative thereof, and preparation method and application thereof 南京大学 2021-07-27 CN disclosed
US-20200232005-A1 Methods of Producing and Using Single-Stranded Deoxyribonucleic Acids and Compositions for Use in Practicing the Same TAKARA BIO USA, INC. 2020-07-23 US disclosed
US-5223619-A Catalytic cyclization A/S GEA FARMACEUTISK FABRIK (DK) 1993-06-29 US disclosed
US-5213972-A Production of thymidine and deoxyuridine, intermediates for AZT CHEMGEN CORPORATION (US) 1993-05-25 US disclosed
EP-0504279-A4 FERMENTATION PROCESS FOR THE PRODUCTION OF PYRIMIDINE DEOXYRIBONUCLEOSIDES 1993-02-17 EP disclosed
WO-1992020816-A1 DETERMINATION OF PRODRUGS METABOLIZABLE BY THE LIVER AND THERAPEUTIC USE THEREOF YALE UNIVERSITY (US) 1992-11-26 WO disclosed
EP-0504279-A1 FERMENTATION PROCESS FOR THE PRODUCTION OF PYRIMIDINE DEOXYRIBONUCLEOSIDES. CHEMGEN CORP (US) 1992-09-23 EP disclosed
EP-0464112-A1 A PROCESS FOR THE PREPARATION OF 9-SUBSTITUTED GUANINE DERIVATIVES AND INTERMEDIATES FOR USE IN THE PROCESS. GEA FARMACEUTISK FABRIK AS (DK) 1992-01-08 EP disclosed
WO-1991009130-A1 FERMENTATION PROCESS FOR THE PRODUCTION OF PYRIMIDINE DEOXYRIBONUCLEOSIDES CHEMGEN CORPORATION (US) 1991-06-27 WO disclosed
WO-1990011283-A1 A PROCESS FOR THE PREPARATION OF 9-SUBSTITUTED GUANINE DERIVATIVES AND INTERMEDIATES FOR USE IN THE PROCESS A/S GEA FARMACEUTISK FABRIK (DK) 1990-10-04 WO disclosed
EP-0303437-A2 Platinum triamine compounds containing nucleotides or nucleosides as antitumor agents ENGELHARD CORPORATION (US) 1989-02-15 EP disclosed