SCHEMBL6748980

SCHEMBL6748980

CC(O)n1c(/C=C/c2nc3ccccc3[nH]2)nc2ccccc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RAB9A P51151 10/20 0.50
▸ KDM4E B2RXH2 10/20 0.50
▸ ALDH1A1 P00352 9/20 0.50
▸ SMN1; SMN2 Q16637 9/20 0.50
▸ NPC1 O15118 9/20 0.50
▸ HPGD P15428 6/20 0.50
▸ GAA P10253 6/20 0.50
▸ GLA P06280 5/20 0.50
▸ TP53 P04637 4/20 0.50
▸ L3MBTL1 Q9Y468 4/20 0.50
▸ MEN1 O00255 7/20 0.49
▸ KMT2A Q03164 7/20 0.49
▸ PKM P14618 3/20 0.49
▸ HSP90AA1 P07900 1/20 0.49
▸ MAPT P10636 8/20 0.48
▸ PDE10A Q9Y233 1/20 0.46
▸ HTT P42858 6/20 0.45
▸ LMNA P02545 5/20 0.45
▸ NFKB1 P19838 2/20 0.45
▸ NFKB2 Q00653 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5517096 0.75 KDM4E (0.49) RAB9AKDM4EALDH1A1SMN1; SMN2NPC1
SCHEMBL5517093 0.75 KDM4E (0.49) RAB9AKDM4EALDH1A1SMN1; SMN2NPC1
SCHEMBL29539476 0.74 ALDH1A1 (0.81) RAB9AKDM4EALDH1A1SMN1; SMN2NPC1
SCHEMBL1086983 0.74 ALDH1A1 (0.81) RAB9AKDM4EALDH1A1SMN1; SMN2NPC1
SCHEMBL1086985 0.74 ALDH1A1 (0.81) RAB9AKDM4EALDH1A1SMN1; SMN2NPC1
SCHEMBL13479982 0.74 ALDH1A1 (0.57) RAB9AKDM4EALDH1A1SMN1; SMN2NPC1
SCHEMBL6748982 0.70 NPC1 (0.52) RAB9AKDM4EALDH1A1SMN1; SMN2NPC1
SCHEMBL10881848 0.70 AURKA (0.41) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL28820772 0.68 ALDH1A1 (0.66) RAB9AKDM4EALDH1A1SMN1; SMN2NPC1
SCHEMBL29881928 0.68 ALDH1A1 (0.66) RAB9AKDM4EALDH1A1SMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6710024-B2 Washing active preparation BASF AKTIENGESELLSCHAFT (DE) 2004-03-23 — — US disclosed
US-20030109414-A1 Washing active preparation BASF AKTIENGESELLSCHAFT (DE) 2003-06-12 — — US disclosed
EP-0209840-B1 LAYERED SILICATES HAVING A REDUCED SWELLING POWER, PROCESS FOR THEIR PREPARATION AND THEIR USE IN WASHING AND CLEANING AGENTS Henkel Kommanditgesellschaft auf Aktien (DE) 1992-01-02 — — EP disclosed
EP-0157320-B1 MANUAL AND MECHANICAL APPLICABLE COLD WASHING AGENT Henkel Kommanditgesellschaft auf Aktien (DE) 1991-10-02 — — EP disclosed
US-5021182-A N,N,N',N'-Tetraacetylene diamine and pentaacetyl glucose; disinfecting laundry at low washing temperatures Epp, Roman A. (DE) 1991-06-04 — — US disclosed
US-4755319-A Mixing crystallized aluminosilicate moist from production with other ingredients, recovering product HENKEL KOMMANDITGELLSCHAFT AUF AKTIEN (DE) 1988-07-05 — — US disclosed
EP-0266379-A1 WASHING AGENTS EPP, Roman A. (DE) 1988-05-11 — — EP disclosed
US-4737306-A MIXED CRYSTAL SYSTEM KENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1988-04-12 — — US disclosed
WO-1987006951-A1 WASHING AGENTS EPP, ROMAN, A. (DE) 1987-11-19 — — WO disclosed
EP-0209840-A2 Layered silicates having a reduced swelling power, process for their preparation and their use in washing and cleaning agents Henkel Kommanditgesellschaft auf Aktien (DE) 1987-01-28 — — EP disclosed
US-4110242-A SOLIDS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1978-08-29 — — US disclosed
US-4083793-A ETHYLENE OXIDE FATTY ALCOHOL ADDUCT, POLYOXYETHYLENE GLYCOL MODIFIED WITH FATTY ALCOHOL, SODIUM SOAP, SODIUM ALKYLBENZENESULFONATE HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DT) 1978-04-11 — — US disclosed
US-4003841-A Coated stabilized bleach activators, process and washing compositions HENKEL & CIE G.M.B.H. (DT) 1977-01-18 — — US disclosed
US-3985670-A Liquid regulated-foam detergent compositions HENKEL & CIE G.M.B.H. (DT) 1976-10-12 — — US disclosed
US-3975280-A Storage-stable, readily-soluble detergent additives, coating compositions and process HENKEL & CIE G.M.B.H. (DT) 1976-08-17 — — US disclosed
US-3965024-A Washing agent compositions and washing assistant composition containing phosphonopolycarboxylate sequestering agents HENKEL & CIE G.M.B.H. (DT) 1976-06-22 — — US disclosed
US-3962116-A COMPOSITIONS OF OPTICAL BRIGHTNESS AND ALUMINOSILICATES AND METHODS OF THEIR PRODUCTION HENKEL & CIE G.M.B.H. (DT) 1976-06-08 — — US disclosed
US-3954643-A SULFONATE SURFACTANT, FATTY ACID SOAP, BUILDER HENKEL & CIE GMBH (DT) 1976-05-04 — — US disclosed
US-3943178-A WASHING AGENT HENKEL & CIE GMBH (DT) 1976-03-09 — — US disclosed
US-3931033-A ETHOXYLATED ALCOHOL, ALKALI METAL SOAP, SEQUESTERANT, SOLVENT, WATER HENKEL & CIE G.M.B.H. (DT) 1976-01-06 — — US disclosed
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